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MTHFR: THE TERRIBLE - but what is the problem I see with MTHFR SNPs? Inflammation caused by homocysteine! If you have high homocysteine, you get high inflammatory cytokine release. The only way to balance it out is reduced glutathione and filling the holes of the methylation cycle. Do this and watch your symptoms disappear!
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Compare the products below, including their ingredients and available forms. Your care team can help you choose one or more options for your needs.
Explore supplements Dr. Purser discusses alongside inflammation and antioxidant support.
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Methylation support
Dr. Purser discusses these supplements in relation to MTHFR.
MTHFR Daily and Hydroxy B12 + Folinic Acid are alternatives. Your folate, vitamin B12, and genetic results can help your clinician choose between them.
Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.
— A Guide by the World’s Leading Homocysteine Expert For more than four decades as a practicing physician, I have watched thousands of patients cycle through conventional autoimmune treatments that address symptoms but never touch the fire underneath. Rheumatoid arthritis flares, lupus rashes, multiple sclerosis relapses, Hashimoto’s thyroiditis, fibromyalgia pain—these are not random. They share a common, often overlooked biochemical pathway: MTHFR mutations leading to elevated homocysteine that supercharges autoimmune inflammation . This is not fringe theory. It is the clinical reality I hav