← Genes & pathways

Gene & pathway reference

DIO1

DIO1 is the gene name for Deiodinase, Iodothyronine Type I. Learn what a specific result could mean and what to ask about it.

Based on teaching by Dan Purser, MD. How we prepare these guides

Updated Sep 17, 2026 · Educational reference

Start here

DIO1 is the gene name for Deiodinase, Iodothyronine Type I. Learn what a specific result could mean and what to ask about it.

How this gene connects

You may see DIO1 discussed alongside Cardiovascular, Vascular function. These are topics to explore, not a diagnosis or a measurement of how the pathway works in your body.

Understanding a result

A gene name is only a starting point. Check which exact variant your report measured and ask what it means for you. Your symptoms and family history matter. Many common variants do not cause disease.

Nutrients and next steps

A genetic finding cannot show a nutrient deficiency or tell you how much of a supplement to take. Bring the original report to your clinician and review it with current nutrient and health findings.

Questions for your visit

Is this a common marker, a pathogenic variant, or an uncertain finding? Does it change my care? Would confirmation or genetic counseling be useful?

Variant lookup

These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.

Names you may see

Deiodinase, Iodothyronine Type I