THE TEACHING CONNECTION
Factor V Leiden concerns clot regulation
Factor V Leiden concerns clot regulation
F5 encodes coagulation factor V. The well-characterized Factor V Leiden variant, rs6025, can make factor V less responsive to an anticoagulant control mechanism, increasing susceptibility to venous clots. It does not mean the body cannot make factor V.
Putting the pieces together
Dr. Purser highlights this pathway when discussing clotting history and oral estrogen. The clinical importance depends on the confirmed result, whether one or two copies are present, previous clots and other risk factors. Discuss hormone and medication choices with the prescribing clinician rather than starting aspirin or an anticoagulant from an encyclopedia page.
A question to bring to your visit
Does my confirmed Factor V Leiden result affect hormone choices or clot-prevention planning?
Variant lookup
These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.
Names you may see
Factor V · Factor V Leiden
EXPLORE WITH YOUR CARE TEAM
Supplements to explore
Compare the products below, including their ingredients and available forms. Your care team can help you choose one or more options for your needs.
CAPSULES & LIQUID
Glutathione options
Explore supplements Dr. Purser discusses for methylation and antioxidant support.
Choose between capsule and liquid forms with your clinician.
Tell your care team which supplements and medicines you already take. Check the product page for current ingredients, prices, and availability.
