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Gene & pathway reference · FROM DR. PURSER’S TEACHING

GSTO2

GSTO2 encodes glutathione S-transferase omega 2, a redox enzyme with dehydroascorbate reductase activity that connects glutathione chemistry with vitamin C recycling. It is a separate gene from GSTO1.

Based on teaching by Dan Purser, MD. How we prepare these guides

Updated Sep 23, 2026 · Educational reference

THE TEACHING CONNECTION

A distinct member of the glutathione network

A distinct member of the glutathione network

GSTO2 encodes glutathione S-transferase omega 2, a redox enzyme with dehydroascorbate reductase activity that connects glutathione chemistry with vitamin C recycling. It is a separate gene from GSTO1.

Putting the pieces together

Dr. Purser’s notes connect GSTO2 with lung-related oxidative stress. This provides a teaching link to exposure history and antioxidant demand, not a diagnosis of COPD or proof that a supplement prevents lung damage. Respiratory symptoms need assessment on their own clinical merits.

A question to bring to your visit

How do breathing symptoms, smoking or other exposures and actual lung findings fit this discussion?

Variant lookup

These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.

Names you may see

Glutathione S-transferase omega 2