IL-17A rs2275913

Understand the connection

IL-17A is part of the Th17 immune pathway and helps organize responses at barrier tissues. It can stimulate other cells to release signals that recruit neutrophils.

Follow the pathway

Dr. Purser discusses rs2275913, an IL17A promoter variant, alongside psoriasis, inflammatory joint disease, and inflammatory bowel disease. He explains how IL-23 can help sustain the Th17 response. A research association is different from a diagnosis or a reason to select a medicine.

Bring these questions to your visit

Ask which result is being discussed: a genetic variant, a measured protein level, or a diagnosed condition. How does it fit with your symptoms and other tests? Dr. Purser discusses antioxidant support alongside these pathways; ask how any supplement would fit with your medicines and care plan.