Total T4 — lab reference
In the reference guideAffected by thyroid-binding globulin, pregnancy, estrogen, and medications.
THE PURSER WELLNESS ENCYCLOPEDIA
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What’s searchable?Affected by thyroid-binding globulin, pregnancy, estrogen, and medications.
Correct for albumin when appropriate or measure ionized calcium.
Fasting, Gilbert syndrome, hemolysis, and liver disease may alter result.
Ask your clinician to review albumin, globulin, and electrophoresis when indicated.
Screening measure, not a stand-alone treatment target.
Binding abnormalities and severe illness may affect some free-hormone assays.
Affected by binding proteins and nonthyroidal illness.
Ask your clinician to read this result with iron, transferrin saturation, and ferritin.
No universal wellness target. Ask your clinician to read this result with B12, folate, B6, kidney, thyroid, genetics, and medications.
<10 severe deficiency; 10-19 mild-moderate deficiency. Toxicity assessment requires clinical context.
Morning collection preferred for men. Method and age matter; confirm unexpected low values.
No single normal cutoff fits every patient. Ask your clinician to use age, baseline, trend, prostate size, risk factors, and shared decision-making.
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