Let’s explore “renal fibrosis”

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling.

Dealing with chronic kidney disease (CRF) or end-stage renal disease (ESRD)? 🩺 The real culprit may not be what you think—high homocysteine levels are a major, often overlooked cause. This triggers the release of harmful cytokines like IL-8

Glutathione and Cytokines: A Hidden Cause of Renal Disease Did you know the cause of end-stage renal disease, often left untested, is high homocysteine? When homocysteine levels spike, it triggers the release of damaging cytokines like IL-

Did you know the cause of end-stage renal disease, often left untested, is high homocysteine? When homocysteine levels spike, it triggers the release of damaging cytokines like IL-8 and MCP-1, leading to kidney failure, high blood pressure

TGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effects can include both regulation of inflammation and promotion of fibrosis.

Explore transforming growth factor-beta 1, tissue repair, fibrosis, systemic sclerosis, and scarring.

The Overlooked Link Between MTHFR Mutations, Hyperhomocysteinemia, PCOS, Fibromyalgia, Chronic Inflammation, and Renal Decline — and Why Precision Genetic Testing May Be the Missing Step

PURSER WELLNESSCan Glutathione Reverse Kidney Disease, Lower Blood Pressure, and Calm Cytokine Storms? What High HA conversation with Dr. Purser

The Overlooked Link Between MTHFR Mutations, Hyperhomocysteinemia, PCOS, Fibromyalgia, Chronic Inflammation, and Renal Decline — and Why Precision Genetic Testing May Be the Missing Step https://danpursermd.substack.com/p/can-glutathione-reverse-kidney-disease?utm_source=youtube

🚨 Homocysteine might be the most dangerous thing your doctor isn’t checking. It’s been linked to kidney failure, dialysis, hypertension, strokes, heart attacks, melanoma, and renal cancer. But it’s not the homocysteine itself—it’s the cytok

PURSER WELLNESSWhat is the true harm of high homocysteine?A conversation with Dr. Purser

🚨 Homocysteine might be the most dangerous thing your doctor isn’t checking. It’s been linked to kidney failure, dialysis, hypertension, strokes, heart attacks, melanoma, and renal cancer. But it’s not the homocysteine itself—it’s the cytokines it triggers, like IL-8 and MCP-1, that do the damage. And if you’ve got any of the 17 key genetic SNPs, you’re at serious risk. You may not be able to lower homocysteine directly—but you can shut down those cytokines with the right nutrients and VARS Glutathione. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Inflammation, hydration, liver synthesis, renal loss, and nutrition affect result.

Renal threshold, SGLT2 inhibitors, pregnancy, and hyperglycemia matter.