Every woman with PCOS I’ve ever tested has a homocysteine problem...
That’s what Dr. Dan Purser says — and it might explain why so many women with PCOS struggle with pain, inflammation, fatigue, and even kidney or blood pressure issues.
Hom
Two big genetic problems I see all the time 👇
- Inflammation (homocysteine, PEMT)
- Gut & liver issues (SIBO, colitis, diarrhea)
Sometimes people have both… and it’s brutal.
Genetics might not be the answer to everything—
but it’s the start
Discover how a common genetic variant in the PEMT gene can block your body’s ability to make phosphatidylcholine — leading to chronic pancreatitis, even if you’ve never touched alcohol.
Mast Cell Activation Syndrome (MCAS) often flares when oxidative stress is high, pushing mast cells to release histamine and inflammatory cytokines. Superoxide Dismutase (SOD) is your body’s first defense against that stress—neutralizing su
Happy Halloween from me and Denise! 🎃👻
Denise is rocking Snow White while I’m channeling my inner cowboy, but the real magic happens when you book a CMA Consult with me. That’s the ultimate trick-or-treat for your health—no sugar crash, ju
Yes—your genetics can directly cause vitamin deficiencies. Certain SNPs lower your body’s ability to process or make key nutrients, like MTHFR reducing folate use, PEMT lowering phosphatidylcholine production for gut and liver health, and SOD decreasing antioxidant defenses against free radicals. These deficiencies drive inflammation, fatigue, and chronic illness, but with the right genetic and intracellular testing, you can target them and supplement with the exact forms your body needs
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
Twitter: https://twitter.com/realdanpursermd
YouTube: https://www.youtube.com/danpursermd
Instagram: https://www.instagram.com/danpurser.md
Pinterest: https://www.pinterest.com/danpursermd
When Justace first had CMA testing done, Dr. Purser told him he was malnourished—even though he was a young athlete eating constantly. The results showed real deficiencies that explained why he struggled to gain and maintain weight. After following Dr. Purser’s protocol, he not only put on healthy weight more easily but no longer had to force himself to eat as much. He now encourages others, especially younger people, to get tested early to avoid genetic breakdowns later in life.
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
Twitter: https://twitter.com/realdanpursermd
YouTube: https://www.youtube.com/danpursermd
Instagram: https://www.instagram.com/danpurser.md
Pinterest: https://www.pinterest.com/danpursermd
PD 80/20 is a supplement designed to raise three key hormones in women—DHEA, pregnenolone, and testosterone. It’s especially useful for restoring testosterone naturally, though it doesn’t typically resolve vaginal dryness unless paired with other therapies. Safe and effective, it gives women an accessible way to boost hormone balance.
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
Twitter: https://twitter.com/realdanpursermd
YouTube: https://www.youtube.com/danpursermd
Instagram: https://www.instagram.com/danpurser.md
Pinterest: https://www.pinterest.com/danpursermd
Patients often ask if they should stop supplements before an intracellular CMA test, and the answer is no. The test measures nutrient status inside your cells over the last 90–100 days, so stopping vitamins right before won’t change the results. At most, you might skip your dose a few hours before the draw, but it’s not necessary—CMA still provides an accurate snapshot of your nutrient levels while you’re on your current routine.
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
Twitter: https://twitter.com/realdanpursermd
YouTube: https://www.youtube.com/danpursermd
Instagram: https://www.instagram.com/danpurser.md
Pinterest: https://www.pinterest.com/danpursermd
MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialize
Search looks for your words in titles, descriptions, available articles, learning guides, and video captions when available. The closest matches appear first. Duplicate posts are grouped, with links to other places you can read or watch them. Books, chapters, and reports have topic guides here; the original files and full book text are not available in this encyclopedia. Subscriber posts include a title and public summary; open Substack to read the full post.