Let’s explore “Cytokines”

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling.

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

Dealing with chronic kidney disease (CRF) or end-stage renal disease (ESRD)? 🩺 The real culprit may not be what you think—high homocysteine levels are a major, often overlooked cause. This triggers the release of harmful cytokines like IL-8

Struggling with high blood pressure that just won’t budge—even with multiple meds? 😩💊 It might be due to genetic issues causing high homocysteine 🧬, which can stiffen your arteries through IL-8 and MCP-1 cytokines 🧪🫀. I’ve seen patients dr

🚨 High Homocysteine? Here’s What You Need to Know! 🚨 If you’ve got genetically high homocysteine, lowering it isn’t as simple as you think. But there’s a way to reduce the inflammation it causes! 🧪🔥 ✅ Homocysteine triggers cytokines like

If you’ve got genetically high homocysteine, lowering it isn’t as simple as you think. But there’s a way to reduce the inflammation it causes! 🧪🔥✅ Homocysteine triggers cytokines like IL-8 & MCP-1✅ The key? Glutathione—but not just any kind

People often ask me the best natural way to lower blood pressure. My answer? Glutathione. High doses can help reduce artery inflammation by stabilizing monocytes that release harmful cytokines, which can lead to high blood pressure. Not a f

Did you know the cause of end-stage renal disease, often left untested, is high homocysteine? When homocysteine levels spike, it triggers the release of damaging cytokines like IL-8 and MCP-1, leading to kidney failure, high blood pressure

Homocysteine- a crazy inflammatory molecule in your body, critical for the production of endogenous glutathione, stimulates the creation of bad cytokines that cause inflammation. Check your IL-8 level and take lots of Reduced Glutathione,

THIS IS SURPRISINGLY ACCURATE. EXCEPT IT IS NOT COMPLETE -- DOESN'T TELL THE WHOLE STORY. What happens to local molecular temperature when you remove the super oxide? What happens to inflammatory cytokines? What does heat and inflammatio

PURSER WELLNESSThe Hidden Molecule Driving Inflammation: Understanding the Purser Model of HomocysteineFrom the reading room

…age. Instead, it acts as a marker of cytokine sensitivity . Cytokines are inflammatory signaling molecules released by immune cells. When homocysteine rises, it can trigger immune cells—especially monocytes and endothelial cells—to release …

…xidant network. Monocytes are immune cells that can release cytokines when they receive stress or danger signals. Follow the pathway Dr. Purser discusses reactive oxygen species, NF-κB, NLRP3, and the cytokines IL-8/CXCL8 and CCL2/MCP-1. H…