VKORC1
Some search terms matchedVKORC1 encodes vitamin K epoxide reductase, part of the vitamin K recycling system used in activating clotting proteins. It is not simply a vitamin K receptor.
Also called: Vitamin K Epoxide Reductase Complex Subunit 1
Recycling vitamin K a…
Understanding a nutrient deficiency
Some search terms matchedHow the Purser approach moves from a nutrient finding to priorities, a manageable plan and reassessment.
Also called:
From a laboratory flag to a useful plan
Start with your original CMA report: check its date, values, and the lab’s catego…
How to read a laboratory report
Some search terms matchedSeparate the gene, variant, measured value and clinical interpretation—and learn which questions to bring to your visit.
Also called:
Keep the original result in view
Start with your original report: check the date, units, the lab’s range,…
SLC19A1
Some search terms matchedEncodes the reduced folate carrier, a protein involved in transporting folates into cells.
Also called: RFC1, reduced folate carrier, folate transport
Folate transport is part of the story
Dr. Purser’s folate map includes transport as well …
ALPL
Some search terms matchedALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme important to bone and tooth mineralization and vitamin B6 metabolism. Persistently low alkaline phosphatase can deserve a different evaluation from a general nutrient deficienc…
CD40LG
Some search terms matchedCD40LG encodes CD40 ligand, which binds CD40 and supports communication needed for effective antibody responses. It is on the X chromosome, which changes how some genetic results must be interpreted.
Also called:
The ligand that helps acti…
IL16
Some search terms matchedIL16 encodes interleukin-16, a cytokine involved in attracting and influencing immune cells, including CD4-expressing cells. Its recruitment role helps separate it from other numbered interleukins.
Also called:
A cytokine involved in immun…
IL17A
Some search terms matchedIL17A encodes interleukin-17A, a cytokine involved in defense at tissue barriers and inflammatory signaling. It belongs to the Th17 pathway, which is supported by signals including IL-23.
Also called:
Th17 signaling and persistent inflamma…
IL18
Some search terms matchedIL18 encodes interleukin-18, a cytokine that can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP.
Also called:
An inflammatory signal that connects to int…
IL18R1
Some search terms matchedIL18R1 encodes a component of the receptor for IL-18. It works with an accessory component, IL18RAP, to support IL-18 signaling.
Also called:
The binding side of the IL-18 receptor
IL18R1 encodes a component of the receptor for IL-18. It w…
IL18RAP
Some search terms matchedIL18RAP encodes an accessory protein in the IL-18 receptor complex. The receptor needs coordinated components to translate an extracellular signal into a cellular response.
Also called:
The accessory component of IL-18 signaling
IL18RAP en…
IL4
Some search terms matchedIL4 encodes interleukin-4, a cytokine involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself.
Also calle…
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