Let’s explore “CD14 & fluctuating blood pressure”

KIT encodes a receptor tyrosine kinase that responds to stem cell factor. It participates in blood-cell development and mast-cell biology, making the exact variant and testing context especially important.

SERPINE1 makes PAI-1, a protein involved in breaking down blood clots. You may also see PAI4G used for this pathway.

VDR encodes the vitamin D receptor, which helps regulate gene activity in response to active vitamin D. A receptor variant does not by itself mean receptors are absent or that the blood vitamin D level is low.

IL6R encodes the interleukin-6 receptor. Membrane-bound and soluble receptor pathways help explain why IL-6 biology involves more than the amount of cytokine in a single blood sample.

MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health. While they don’t directly cause blood sugar crashes, understanding your genetics, nutrition, sleep, stress, and nutrient status c

Explore HbA1c, red blood cell turnover, hemoglobin variants, blood loss, hypoglycemia, and factors that may affect a low A1C result.

MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health. While they don’t directly cause blood sugar crashes, understanding your genetics, nutrition, sleep, stress, and nutrient status

PURSER WELLNESSMTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving SweetsA conversation with Dr. Purser

MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.” In this video, we break down exactly why this happens: How MTHFR/methylation issues impair ATP (energy) production at the cellular level Why your body desperately reaches for quick glucose The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage The downstream effects on antioxidants, DNA repair, and overall energy How to finally break the cycle: Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests) Why our MTHFR Daily multivitamin was specifically formulated for this The power of CMA intracellular testing Intermittent fasting (12–16 hrs) Fasted cardio (even just a brisk walk) High-protein, real-food diet with minimal processed sugars If you’re tired of the sugar rollercoaster and want stable energy, this is for you. Links: Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious! #MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

What if the answers you've been searching for aren't found in another prescription—but inside your own cells? Most lab tests tell you what's circulating in your blood. But what if your cells are telling a different story? A Cellular Micro

PURSER WELLNESSFrom Fibromyalgia to Feeling FantasticA conversation with Dr. Purser

In this consultation review, Jackson sat down with longtime Purser Wellness patient Lois Schweigert to go over her latest intracellular micronutrient (CMA) test results. After years of dealing with fibromyalgia, pain, gut issues, and inconsistent energy, Lois has made remarkable progress. Her newest CMA shows ZERO deficiencies — her best results ever — and it perfectly matches how great she’s been feeling. We discuss: • Her consistent weight training and dramatically improved recovery (thanks to catalase!) • Key optimization tweaks: amino acids, omega-3s, chromium, inositol, and glutathione • Blood sugar stability • Sleep support and overnight recovery • How trauma & stress affect your nutrient levels • Why intracellular testing is so unique and powerful If you’re dealing with chronic symptoms, poor workout recovery, or just want to optimize your health, this conversation is packed with practical insights from real patient results. 👉 Ready to get your own CMA? Visit danpursermd.com or comment “CMA” below and we’ll send you info. #PurserWellness #Fibromyalgia #RootCauseHealth #CMATest #FunctionalMedicine This video is for educational purposes only and is based on Dr. Dan Purser’s protocols. Not medical advice. Always consult with your healthcare provider. Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSHow To Know If You Have High Homocysteine?A conversation with Dr. Purser

High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a blood test can measure homocysteine directly, while a CMA with Redox uncovers the vitamin deficiencies driving it. For genetic causes, the DRP Genetics panel screens 15–16 of the 17 known SNPs that can cause permanently high homocysteine. If your levels are fixed by genetics, reduced glutathione and targeted B vitamins (like MTHFR Daily) are key to balancing the

PURSER WELLNESSHave Fibromyalgia? This video is for you - let’s get to the root.A conversation with Dr. Purser

The real root of fibromyalgia? It’s not just pain — it’s copper. We’ve uncovered that fibromyalgia is often driven by genetic mutations (like CBS, GAD1, GAD2) that affect how your body handles copper. The copper builds up in your blood but never makes it into your cells — leading to widespread pain, inflammation, and migraines.