THE PURSER WELLNESS ENCYCLOPEDIA

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A RELATED COURSEFatigue: asking better questions

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New to this subject? Start with this free introduction.What Causes Chronic Fatigue Syndrome?

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YouTubeAug 6, 2026

OVER-METHYLATION - Are Your B Vitamins Hurting You?

Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

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FacebookAug 4, 2026

Feeling tired all the time is often dismissed as stress, aging, or a busy schedule.

Feeling tired all the time is often dismissed as stress, aging, or a busy schedule. But persistent fatigue can have many possible causes, including nutritional issues that may not be obvious from routine testing. A Cellular Micronutrient

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FacebookJul 22, 2026

What if the hardest part of living with chronic pain isn't only the pain itself?

What if the hardest part of living with chronic pain isn't only the pain itself? For many people, it's the mental fog. The constant distraction. The struggle to concentrate. The feeling that your mind isn't as sharp as it used to be.

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FacebookJul 21, 2026

Have you ever dropped your keys, your phone, or a cup of coffee and wondered, "What's happening to me?"

Have you ever dropped your keys, your phone, or a cup of coffee and wondered, "What's happening to me?" For many people living with fibromyalgia, it's not just the pain that disrupts daily life. Changes in coordination, grip strength, br

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