THE TEACHING CONNECTION
Managing folate inside cells
Managing folate inside cells
GGH encodes gamma-glutamyl hydrolase, which removes glutamate residues from folate compounds. This affects folate handling and helps explain why folate metabolism includes retention and processing as well as intake.
Putting the pieces together
Dr. Purser notes an indirect connection to homocysteine. Follow that connection through the wider folate network, including MTHFR, MTR and nutrient status, rather than interpreting GGH as a direct homocysteine reading. Some medicines also interact with folate pathways and belong in the review.
Where the VARS Triad and MTHFR Daily fit
If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and the VARS Triad: VARS Glutathione, VARS SOD, and VARS Catalase. He gives glutathione a central place in his approach to antioxidant support.
A gene result alone cannot tell you that you need these products or that they will treat a condition. Review your current results, medicines, goals, and tolerance with your clinician before choosing a product or dose.
A question to bring to your visit
Do my folate, B12 and homocysteine findings support a folate-handling concern?
Variant lookup
These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.
Names you may see
Gamma-Glutamyl Hydrolase
EXPLORE WITH YOUR CARE TEAM
Supplements to explore
Compare the products below, including their ingredients and available forms. Your care team can help you choose one or more options for your needs.
Explore supplements Dr. Purser discusses alongside inflammation and antioxidant support.
CAPSULES & LIQUID
Glutathione options
Dr. Purser discusses these supplements in relation to GGH.
Some genetic results may make these options more relevant to you. Review your full genetic report with your clinician before choosing a supplement.
SUPPLEMENT OPTIONS
VARS SOD
Ask your clinician how this option fits your results and current medicines.
SUPPLEMENT OPTIONS
VARS Catalase Support
Ask your clinician how this option fits your results and current medicines.
COMPARE YOUR OPTIONS
Methylation support
MTHFR Daily and Hydroxy B12 + Folinic Acid are alternatives. Your results can help your clinician choose between them.
Tell your care team which supplements and medicines you already take. Check the product page for current ingredients, prices, and availability.
