← Genes & pathways

Gene & pathway reference · FROM DR. PURSER’S TEACHING

IL15

IL15 encodes a cytokine involved in the survival and activity of immune cells, including natural killer cells and memory CD8 T cells. Its receptor system includes IL15RA.

Based on teaching by Dan Purser, MD. How we prepare these guides

Updated Sep 23, 2026 · Educational reference

THE TEACHING CONNECTION

Supporting immune-cell survival

Supporting immune-cell survival

IL15 encodes a cytokine involved in the survival and activity of immune cells, including natural killer cells and memory CD8 T cells. Its receptor system includes IL15RA.

Putting the pieces together

Dr. Purser discusses IL-15 in relation to persistent autoimmune activity and memory T-cell survival. This is a biological framework for understanding an established immune condition, not proof that long-lasting symptoms are caused by excess IL-15.

Where the VARS Triad and MTHFR Daily fit

If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and the VARS Triad: VARS Glutathione, VARS SOD, and VARS Catalase. He gives glutathione a central place in his approach to antioxidant support.

A gene result alone cannot tell you that you need these products or that they will treat a condition. Review your current results, medicines, goals, and tolerance with your clinician before choosing a product or dose.

A question to bring to your visit

Is there evidence of a persistent immune disorder that makes this pathway relevant?

Variant lookup

These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.

Names you may see

IL-15 · Interleukin 15