← Genes & pathways

Gene & pathway reference · FROM DR. PURSER’S TEACHING

MMP3

MMP3 encodes matrix metalloproteinase 3, an enzyme involved in breaking down components of the extracellular matrix. Controlled remodeling is part of repair, while excess activity can accompany inflammatory tissue damage.

Based on teaching by Dan Purser, MD. How we prepare these guides

Updated Sep 23, 2026 · Educational reference

THE TEACHING CONNECTION

Remodeling the tissue around cells

Remodeling the tissue around cells

MMP3 encodes matrix metalloproteinase 3, an enzyme involved in breaking down components of the extracellular matrix. Controlled remodeling is part of repair, while excess activity can accompany inflammatory tissue damage.

Putting the pieces together

Dr. Purser places MMP3 in the tendon, joint and healing conversation. Joint examination, injury history and inflammatory findings help distinguish mechanical problems from active inflammatory disease. A panel SNP cannot tell you that MMP3 is absent or diagnose arthritis or cancer.

A question to bring to your visit

Is my joint problem primarily mechanical, inflammatory or part of a broader connective-tissue pattern?

Variant lookup

These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.

Names you may see

Matrix Metallopeptidase 3