MTHFS | Purser Wellness Encyclopedia

THE TEACHING CONNECTION

Folinic acid has its own processing step

MTHFS encodes an enzyme that converts 5-formyltetrahydrofolate into 5,10-methenyltetrahydrofolate. This places it in folate interconversion; it is not another name for MTHFR or a direct maker of methylfolate.

Putting the pieces together

Dr. Purser’s notes connect MTHFS with folate support and homocysteine. The useful lesson is that the form of folate matters and that several enzymes connect those forms. Discuss the actual product and response alongside B12 and homocysteine findings rather than assigning a folate form solely from rs6495446.

Where the VARS Triad and MTHFR Daily fit

If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and the VARS Triad: VARS Glutathione, VARS SOD, and VARS Catalase. He gives glutathione a central place in his approach to antioxidant support.

A gene result alone cannot tell you that you need these products or that they will treat a condition. Review your current results, medicines, goals, and tolerance with your clinician before choosing a product or dose.

A question to bring to your visit

How does my current folate form enter the pathway, and what evidence supports changing it?

Variant lookup

These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.

rs6495446