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Gene & pathway reference · FROM DR. PURSER’S TEACHING

NQO1

NQO1 is the gene name for NAD(P)H Quinone Oxidoreductase 1. Learn what a specific result could mean and what to ask about it.

Based on teaching by Dan Purser, MD. How we prepare these guides

Updated Sep 23, 2026 · Educational reference

THE TEACHING CONNECTION

Quinone handling within the redox network

Quinone handling within the redox network

Dr. Purser includes NQO1 in the wider redox discussion rather than limiting antioxidant teaching to glutathione. NQO1 participates in quinone reduction, a different enzyme task from superoxide removal by SOD or peroxide handling by catalase.

Putting the pieces together

NQO1 is discussed alongside GST and PON pathways that help handle certain reactive compounds. A gene result cannot show that you were exposed to a toxin or that your body cannot clear it.

Where the VARS Triad and MTHFR Daily fit

If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and the VARS Triad: VARS Glutathione, VARS SOD, and VARS Catalase. He gives glutathione a central place in his approach to antioxidant support.

A gene result alone cannot tell you that you need these products or that they will treat a condition. Review your current results, medicines, goals, and tolerance with your clinician before choosing a product or dose.

A question to bring to your visit

Is this a verified gene finding, a measured exposure or a current redox result—and are we keeping those distinct?

Reading your own results

Bring your original report, current results, health history, and medicines to your visit. This information can help you ask questions, but it cannot diagnose a condition or choose a supplement dose for you.

Variant lookup

These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.

rs1800566

Names you may see

NAD(P)H Quinone Oxidoreductase 1