THE TEACHING CONNECTION
Mineralocorticoid signaling and salt balance
Mineralocorticoid signaling and salt balance
NR3C2 encodes the mineralocorticoid receptor, which responds to hormones such as aldosterone and helps regulate salt and fluid balance. It is distinct from the NR3C1 glucocorticoid receptor.
Putting the pieces together
Dr. Purser groups NR3C2 into the broader stress-response discussion. Its role also makes blood pressure, electrolyte results and relevant medicines important context. A wellness SNP is not evidence that the receptor is missing or that salt, potassium or hormone treatment should be changed.
A question to bring to your visit
Do blood pressure, electrolytes or medicines provide a clinical reason to investigate this pathway?
Variant lookup
These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.
Names you may see
Mineralocorticoid Receptor / Nuclear Receptor Subfamily 3 Group C Member 2
EXPLORE WITH YOUR CARE TEAM
Supplements to explore
Compare the products below, including their ingredients and available forms. Your care team can help you choose one or more options for your needs.
SUPPLEMENT OPTIONS
PS 150
Dr. Purser discusses these supplements in relation to NR3C2.
Some genetic results may make these options more relevant to you. Review your full genetic report with your clinician before choosing a supplement.
Tell your care team which supplements and medicines you already take. Check the product page for current ingredients, prices, and availability.
