GSTO1 belongs to the omega family of glutathione S-transferases. These enzymes participate in redox chemistry, with roles that differ from the better-known GSTM1 and GSTP1 pathways.
Also called: Glutathione S-Transferase Omega 1
An omega-fa…
GSTP1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Pi 1
Using glutathione in conjugation
GSTP1 belongs to the glutathione transferase family. These enzymes use glutathione in conjugation …
GSTT1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Theta 1, GSTT
Using glutathione in conjugation
GSTT1 belongs to the glutathione transferase family. These enzymes use glutathione in con…
MTHFD1 helps move folate between forms used for different jobs in the body.
Also called: Methylenetetrahydrofolate Dehydrogenase 1
Folate has several working forms
Dr. Purser includes MTHFD1 among genes involved in folate interconversion. T…
The homocysteine chapters include MTHFD1L in the wider folate-related genetic map.
Also called: Methylenetetrahydrofolate Dehydrogenase 1-Like
A mitochondrial contribution to one-carbon metabolism
The homocysteine chapters include MTHFD1L i…
NR3C1 encodes the glucocorticoid receptor, which helps tissues respond to cortisol and glucocorticoid medicines. Receptor genetics and measured cortisol levels answer different questions.
Also called: Nuclear Receptor Subfamily 3 Group C Me…
PON1 is discussed in relation to how the body handles some compounds and protects certain fats.
Also called: Paraoxonase 1
A different part of antioxidant handling
PON1 appears in Dr. Purser’s redox and conversion teaching alongside GST and…
PSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.
Also called:…
SERPINE1 makes PAI-1, a protein involved in breaking down blood clots. You may also see PAI4G used for this pathway.
Also called: PAI-1, PAI4G, Plasminogen Activator Inhibitor-1, Plasminogen Activator Inhibitor 1, 4G/5G Polymorphism
Balanci…
SHMT1 connects serine and glycine with folate chemistry.
Also called: Serine Hydroxymethyltransferase 1
Where amino acids meet folate
SHMT1 connects serine and glycine with folate pathways. That is one reason both nutrition and genetics can…
SOD1 helps convert superoxide inside cells as part of the body’s antioxidant defenses.
Also called: Superoxide Dismutase 1
Superoxide defense in its own setting
Dr. Purser teaches SOD as one member of an antioxidant team. SOD1 works primari…
VKORC1 encodes vitamin K epoxide reductase, part of the vitamin K recycling system used in activating clotting proteins. It is not simply a vitamin K receptor.
Also called: Vitamin K Epoxide Reductase Complex Subunit 1
Recycling vitamin K a…
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