Let’s explore “Hirschsprung’s disease & genetics”

Explore SERPINE1 / PAI-1, rs1799889, 4G/5G, fibrinolysis, hyperhomocysteinemia (HHcy), vascular health, and differences between approaches to clotting risk.

Explore tumor necrosis factor-alpha, TNFR1, TNFR2, rs1800629, inflammatory signaling, and treatment comparisons in Purser Wellness teaching.

A fast look at the genetic quirks I came across this week, from odd inherited traits to the ones that can seriously affect health. Clear, curious, and a little alarming.

Dan and Jackson discuss serum testing, intracellular nutrient results, REDOX, and the questions each kind of test addresses.

The MTHFR Sugar Crash Cycle. The answers to the answers to the problems no one else has ever been able to give you. Find the support and help you've been looking for at PurserWellness.com

A subscriber episode exploring questions about MTHFR, nutrient status, and daily energy. Read the public introduction and continue on Substack.

Certain genetic variants can affect MTHFR enzyme activity, which is why understanding your individual biology can change the conversation around nutrition. That is where MTHFR Daily comes in. Designed with methylation support in mind, MTH

You eat something sweet. Your energy shoots up. Then suddenly you are exhausted, foggy, irritable, and reaching for something else to get you through the day. That cycle deserves a closer look. MTHFR variants can influence folate meta

Explore cytokines, chemokines, receptors, and related genes on the comprehensive panel, including CD40LG, IL18R1, DDAH1, RAD50, and SLC19A1.

Explore dimethylarginine dimethylaminohydrolase 1 (DDAH1), asymmetric dimethylarginine (ADMA), nitric oxide, blood vessels, and related blood-vessel pathways.

Explore transsulfuration, methylation, glutathione, genetic variants, cytokines, and possible connections.

Explore the IFNG variant rs2430561, the +874 T/A position, NF-kappa B, and interferon-gamma regulation.