FOLH1 helps break down folate from food so it can be absorbed. This is different from the MTHFR step.
Also called: Folate Hydrolase 1
Folate handling begins before remethylation
Dr. Purser’s genetic chapters include FOLH1 in folate handling…
GAD1 helps your body make GABA, a chemical messenger, from glutamate.
Also called: Glutamate Decarboxylase 1
The glutamate-to-GABA connection
Dr. Purser’s course uses GAD/GABA teaching to explain a connection between excitatory and inhibito…
GPX1 helps cells use glutathione to handle peroxides.
Also called: Glutathione Peroxidase 1
Glutathione has enzyme partners
Dr. Purser teaches the glutathione peroxidase family alongside selenium and antioxidant support. GPX1 helps illustra…
GSTM1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Mu 1
Using glutathione in conjugation
GSTM1 belongs to the glutathione transferase family. These enzymes use glutathione in conjugation …
GSTO1 belongs to the omega family of glutathione S-transferases. These enzymes participate in redox chemistry, with roles that differ from the better-known GSTM1 and GSTP1 pathways.
Also called: Glutathione S-Transferase Omega 1
An omega-fa…
GSTP1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Pi 1
Using glutathione in conjugation
GSTP1 belongs to the glutathione transferase family. These enzymes use glutathione in conjugation …
GSTT1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Theta 1, GSTT
Using glutathione in conjugation
GSTT1 belongs to the glutathione transferase family. These enzymes use glutathione in con…
MTHFD1 helps move folate between forms used for different jobs in the body.
Also called: Methylenetetrahydrofolate Dehydrogenase 1
Folate has several working forms
Dr. Purser includes MTHFD1 among genes involved in folate interconversion. T…
The homocysteine chapters include MTHFD1L in the wider folate-related genetic map.
Also called: Methylenetetrahydrofolate Dehydrogenase 1-Like
A mitochondrial contribution to one-carbon metabolism
The homocysteine chapters include MTHFD1L i…
NR3C1 encodes the glucocorticoid receptor, which helps tissues respond to cortisol and glucocorticoid medicines. Receptor genetics and measured cortisol levels answer different questions.
Also called: Nuclear Receptor Subfamily 3 Group C Me…
PON1 is discussed in relation to how the body handles some compounds and protects certain fats.
Also called: Paraoxonase 1
A different part of antioxidant handling
PON1 appears in Dr. Purser’s redox and conversion teaching alongside GST and…
PSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.
Also called:…
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