CREST is an older name for a pattern of limited cutaneous systemic sclerosis.
Understand the connection
CREST is an older term for a pattern of limited cutaneous systemic sclerosis. The condition can involve blood vessels, skin, digestion,…
Explore multiple sclerosis (MS), central nervous system inflammation, myelin, symptoms, and related immune signals.
Understand the connection
Multiple sclerosis involves immune-mediated injury to myelin and other nervous-system structures.…
Your body’s ability to detox depends on one critical pathway—turning homocysteine into glutathione. But for millions with MTHFR or other genetic SNPs, this process is broken, leaving them vulnerable to toxins, inflammation, and cytokine sto
🚨 Homocysteine might be the most dangerous thing your doctor isn’t checking. It’s been linked to kidney failure, dialysis, hypertension, strokes, heart attacks, melanoma, and renal cancer. But it’s not the homocysteine itself—it’s the cytok
🚨 High homocysteine isn’t just a lab number—it’s a warning sign.
Genes like MTHFR, MTR, MTRR, and GGH can overactivate the methylation cycle and lead to hyperhomocysteinemia, which drives inflammation, stroke risk, and even kidney failure.
🚨 Homocysteine is nasty — but here’s the truth no one tells you. It doesn’t kill you directly — it triggers white blood cells to release IL-8 and MCP-1, which drive inflammation, kidney failure, heart attacks, and strokes. Most doctors don’
🚨 Homocysteine is nasty — but here’s the truth no one tells you.
It doesn’t kill you directly — it triggers white blood cells to release IL-8 and MCP-1, causing inflammation, kidney failure, heart attacks, and strokes. Most doctors don’t ev
Glutathione and Cytokines: A Hidden Cause of Renal Disease
Did you know the cause of end-stage renal disease, often left untested, is high homocysteine? When homocysteine levels spike, it triggers the release of damaging cytokines like IL-…
🧬 MTHFR Mutations, High Homocysteine & Autoimmune Disease: The Hidden Root Cause Most Doctors Miss
For decades, patients with RA, lupus, MS, Hashimoto’s, and fibromyalgia chase symptom relief with meds that never fix the underlying fire.
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🔥 Got high homocysteine? It’s not just about heart health—it’s about inflammation. Track your IL-8 (yes, you can test it!), and take enough glutathione to bring it down—sometimes that means 4, 6, even 8 capsules a day. When IL-8 hits zero,
We're back. That's good. We weren't ever here. We never have done a personal. Yeah, true. Okay. Okay. We are live in a couple places. So, we are. You want to start saying hi to people? Hey everyone, this Dan Perer, Dr. Dan Perer, danpermd.c…
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