…L16 encodes interleukin-16, a cytokine involved in attracting and influencing immune cells, including CD4-expressing cells. Its recruitment role helps separate it from other numbered interleukins.
Also called:
A cytokine involved in immune…
…e involved in defense at tissue barriers and inflammatory signaling. It belongs to the Th17 pathway, which is supported by signals including IL-23.
Also called:
Th17 signaling and persistent inflammation
IL17A encodes interleukin-17A, a cy…
…odes interleukin-18, a cytokine that can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP.
Also called:
An inflammatory signal that connects to interferon …
…ks with an accessory component, IL18RAP, to support IL-18 signaling.
Also called:
The binding side of the IL-18 receptor
IL18R1 encodes a component of the receptor for IL-18. It works with an accessory component, IL18RAP, to support IL-18 …
…eeds coordinated components to translate an extracellular signal into a cellular response.
Also called:
The accessory component of IL-18 signaling
IL18RAP encodes an accessory protein in the IL-18 receptor complex. The receptor needs coord…
…ry responses and fever. Its production and activation are regulated processes, not simply an on/off consequence of having a common SNP.
Also called:
IL-1β and the early inflammatory response
IL1B encodes interleukin-1 beta, a cytokine invo…
…ile its effects depend on the tissue and inflammatory setting.
Also called:
Barrier defense, repair and excess tissue growth
IL22 encodes a cytokine that acts on tissues such as epithelial barriers. It can support barrier defense and repai…
IL23A encodes the p19 subunit of interleukin-23. Together with the p40 subunit encoded by IL12B, it forms a cytokine involved in supporting Th17 responses.
Also called:
The p19 component of IL-23
IL23A encodes the p19 subunit of interleuki…
…also called CD25. It is involved in immune activation and regulatory T-cell biology; a soluble receptor measurement is distinct from a DNA result.
Also called:
CD25 and immune-cell activation
IL2RA encodes the alpha chain of the interleuki…
IL33 encodes interleukin-33, a signal that can act as an alarmin during tissue stress and promote type 2 immune responses. It belongs in a different functional group from chemokines that recruit cells.
Also called:
An alarmin in allergic s…
…involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself.
Also called:
Th2 signaling and allergic pattern…
…5 encodes interleukin-5, a cytokine important to eosinophil growth, survival and activation. Eosinophils are involved in selected allergic and other inflammatory conditions.
Also called:
An eosinophil-focused cytokine
IL5 encodes interleuk…
Search looks for your words in titles, descriptions, available articles, learning guides, and video captions when available. The closest matches appear first. Duplicate posts are grouped, with links to other places you can read or watch them. Books, chapters, and reports have topic guides here; the original files and full book text are not available in this encyclopedia. Subscriber posts include a title and public summary; open Substack to read the full post.