FOLH1 helps break down folate from food so it can be absorbed. This is different from the MTHFR step.
Also called: Folate Hydrolase 1
Folate handling begins before remethylation
Dr. Purser’s genetic chapters include FOLH1 in folate handling…
FOLR1 encodes folate receptor alpha, which helps cells take up folate and has an important role in folate transport at the brain’s barriers. Blood folate and folate availability in the nervous system are not identical measurements.
Also cal…
…sation. Those connections do not make an IBS label, Crohn’s disease or another diagnosis interchangeable, and a common variant is not a substitute for a digestive workup.
A question to bring to your visit
Which part of my history points to …
GAD1 helps your body make GABA, a chemical messenger, from glutamate.
Also called: Glutamate Decarboxylase 1
The glutamate-to-GABA connection
Dr. Purser’s course uses GAD/GABA teaching to explain a connection between excitatory and inhibito…
GPX1 helps cells use glutathione to handle peroxides.
Also called: Glutathione Peroxidase 1
Glutathione has enzyme partners
Dr. Purser teaches the glutathione peroxidase family alongside selenium and antioxidant support. GPX1 helps illustra…
GSTM1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Mu 1
Using glutathione in conjugation
GSTM1 belongs to the glutathione transferase family. These enzymes use glutathione in conjugation …
GSTO1 belongs to the omega family of glutathione S-transferases. These enzymes participate in redox chemistry, with roles that differ from the better-known GSTM1 and GSTP1 pathways.
Also called: Glutathione S-Transferase Omega 1
An omega-fa…
GSTP1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Pi 1
Using glutathione in conjugation
GSTP1 belongs to the glutathione transferase family. These enzymes use glutathione in conjugation …
GSTT1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Theta 1, GSTT
Using glutathione in conjugation
GSTT1 belongs to the glutathione transferase family. These enzymes use glutathione in con…
HLA-DQA1 contributes to an HLA-DQ protein that presents antigen fragments to CD4 T cells. HLA-DQ function depends on pairing with an HLA-DQB chain, so an isolated marker is not a complete HLA type.
Also called: HLADQA1, Human Leukocyte Anti…
IL21 encodes a cytokine involved in regulating lymphocytes, including B-cell responses. It sits within an immune network that connects T-cell help, antibody responses and inflammatory activity.
Also called: IL-21, Interleukin 21
A link betw…
…-23 signals. This connects the gene to the maintenance of Th17-related immune responses, which differ from the Th2 patterns discussed in allergy.
Also called: IL-23R, Interleukin 23 Receptor
The receptor side of the IL-23 pathway
IL23R enco…
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