IL15RA encodes the alpha receptor component for IL-15. It helps present IL-15 to responding immune cells, supporting communication that is important for particular lymphocyte populations.
Also called:
Presenting IL-15 to responding cells
I…
IL16 encodes interleukin-16, a cytokine involved in attracting and influencing immune cells, including CD4-expressing cells. Its recruitment role helps separate it from other numbered interleukins.
Also called:
A cytokine involved in immun…
IL17A encodes interleukin-17A, a cytokine involved in defense at tissue barriers and inflammatory signaling. It belongs to the Th17 pathway, which is supported by signals including IL-23.
Also called:
Th17 signaling and persistent inflamma…
IL18 encodes interleukin-18, a cytokine that can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP.
Also called:
An inflammatory signal that connects to int…
IL18R1 encodes a component of the receptor for IL-18. It works with an accessory component, IL18RAP, to support IL-18 signaling.
Also called:
The binding side of the IL-18 receptor
IL18R1 encodes a component of the receptor for IL-18. It w…
IL18RAP encodes an accessory protein in the IL-18 receptor complex. The receptor needs coordinated components to translate an extracellular signal into a cellular response.
Also called:
The accessory component of IL-18 signaling
IL18RAP en…
IL1B encodes interleukin-1 beta, a cytokine involved in inflammatory responses and fever. Its production and activation are regulated processes, not simply an on/off consequence of having a common SNP.
Also called:
IL-1β and the early infl…
…this barrier-repair discussion?
Variant IDs in the teaching reference: rs1179251, rs2227485, rs2227513
Also called: IL-22, Interleukin 22
Where the VARS Triad and MTHFR Daily fit
If you are exploring homocysteine or cytokines, Dr. Purser ma…
IL23A encodes the p19 subunit of interleukin-23. Together with the p40 subunit encoded by IL12B, it forms a cytokine involved in supporting Th17 responses.
Also called:
The p19 component of IL-23
IL23A encodes the p19 subunit of interleuki…
… has to be interpreted in context rather than used alone to label sarcoidosis.
A question to bring to your visit
Which kind of IL-2 receptor result do I have, and what clinical question was it intended to answer?
Variant IDs in the teaching…
…x findings each been evaluated?
Variant IDs in the teaching reference: rs7044343, rs3939286, rs1929992
Also called: IL-33, Interleukin 33
Where the VARS Triad and MTHFR Daily fit
If you are exploring homocysteine or cytokines, Dr. Purser ma…
… pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself.
Also called:
Th2 signaling and allergic patterns
IL4 encodes interleukin-4, a cytokine involved in Th2 immune responses…
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