Let’s explore “Hailey-Hailey disease & cytokines”

Explore the NLRP3 sensor, inflammasome priming and activation, IL-1 beta, IL-18, and pyroptosis.

Explore TNFSF10, TRAIL, DR4, DR5, apoptosis, immune surveillance, and cell-death signaling and treatment research.

Explore volatile hypertension, autonomic regulation, monocytes, vascular inflammation, and how they may connect.

By Dan Purser MD Pathway-level clinical interpretation focused on inflammatory interaction, likely signs, and likely complications

PURSER WELLNESSWhere To Find Dr. Purser Online (Deplatformed)A conversation with Dr. Purser

Dr. Dan Purser here with an important update from Purser Wellness. Earlier this week we were deplatformed on a major platform right after discussing groundbreaking findings from our homocysteine research — particularly its connections to ASD, ADHD, cytokine issues, and inflammatory conditions like polymyalgia rheumatica (PMR). Despite losing access to our old page (and nearly 200,000 followers), we’re back stronger with a brand new official page! ✅ Follow our new official Facebook page here: https://www.facebook.com/purserwellness We’re keeping things focused and continuing our important work on root-cause wellness, intracellular nutrient deficiencies, genetics, glutathione/SOD balance, and more. ### Where to Stay Connected: - Substack (Daily research articles & in-depth content): https://substack.com/PurserWellness or https://danpursermd.substack.com - YouTube – Live streams and full recordings will continue here (plus TikTok, Instagram, and podcast platforms) Dr. Purser’s message is clear: We will not stop the research. “I’ll quit when I die… and maybe not even then.” If you’ve been following our work on homocysteine, MTHFR, cytokine problems, hormone optimization, and functional medicine protocols, please: - Like and follow the new Facebook page - Subscribe to Substack - Share this video with friends and patients who need this information Thank you for your incredible support during this transition. Your follows and shares help us keep delivering the cutting-edge research no one else is doing. 👉 New Facebook Page: https://www.facebook.com/purserwellness Purser Wellness Root-Cause Medicine • Genetics • Homocysteine Research danpursermd.com #DrDanPurser #PurserWellness #Homocysteine #FunctionalMedicine #RootCauseHealth #CytokineResearch #ASD #ADHD #MTHFR

Why elevated soluble IL-2 receptor levels drive chronic inflammation and pain in sarcoidosis — and what actually helps quiet the fire

Explore interleukin-2, T cells, natural killer cells, immunotherapy, vascular leak syndrome, and effects on the immune system.

PURSER WELLNESSUnable to Detox From Inflammation?A conversation with Dr. Purser

Jackson Larkin, one of our Purser Wellness Coaches discusses the need to support your Inflammatory Marker Genetics and what current supplements help achieve this.

Dr. Purser shares his clinical perspective on homocysteine, methylation, and inflammatory patterns.

PURSER WELLNESSHigh Homocysteine, MTHFR Mutations, and the Inflammation Crisis: The Cardiovascular, Fertility, andA conversation with Dr. Purser

How Elevated Homocysteine, Impaired Methylation, and Glutathione Deficiency May Be Driving PCOS, Chronic Pain, Brain Fog, Stroke Risk, and Detox Failure — and Why Genetic Testing WILL Change the Way https://danpursermd.substack.com/p/high-homocysteine-mthfr-mutations?utm_source=youtube

PURSER WELLNESSWhy does MTHFR correlate with high homocysteine?A conversation with Dr. Purser

Follow Dr. Purser! Did you know your MTHFR gene can impact your homocysteine levels? High homocysteine is linked to heart and brain health—understanding this connection could be the key to solving your mystery medical problems that no doctor or study has been able to figure out. Curious how it all works? Let’s break it down in simple terms. #insulin #genetics #vitamins #Vars #wellness #PEMT #inflammation #glutathione #MicronutrientTesting #FunctionalMedicine #SOD #Homocysteine #ChronicInflammation #MethylationMatters #FunctionalWellness #GeneticTesting #NutrientDeficiency #MTHFR #fibromyalgia #Methylation #DrDanPurser #purserwellness Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSAUTSIM - What is a potential ROOT CAUSE of Autism? Can it be helped?A conversation with Dr. Purser

What I see again and again is an inability to detox caused by failures in the Transsulfuration Pathway. This is your pathway that converts homocysteine to glutathione. If you have MTHFR or 16 other Gene SNPs, you will have problems with this pathway.