THE PURSER WELLNESS ENCYCLOPEDIA

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Gene referenceSep 23, 2026

TNF

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TNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer. Also called: Tumor Necrosis Fact…

Gene referenceSep 23, 2026

SLC19A1

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Encodes the reduced folate carrier, a protein involved in transporting folates into cells. Also called: RFC1, reduced folate carrier, folate transport Folate transport is part of the story Dr. Purser’s folate map includes transport as well …

Gene referenceSep 23, 2026

ALPL

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ALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme important to bone and tooth mineralization and vitamin B6 metabolism. Persistently low alkaline phosphatase can deserve a different evaluation from a general nutrient deficienc…

Gene referenceSep 23, 2026

CCL5

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CCL5, also called RANTES, is a chemokine that helps direct immune-cell movement. Chemokines tell cells where to go, which is different from measuring the total strength of an immune response. Also called: RANTES and immune-cell recruitment…

Gene referenceSep 23, 2026

CD40

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CD40 encodes a receptor that participates in communication between immune cells, including T-cell help for B-cell responses. Its partner is CD40 ligand, encoded by CD40LG. Also called: A conversation between immune cells CD40 encodes a rec…

Gene referenceSep 23, 2026

CD40LG

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CD40LG encodes CD40 ligand, which binds CD40 and supports communication needed for effective antibody responses. It is on the X chromosome, which changes how some genetic results must be interpreted. Also called: The ligand that helps acti…

Gene referenceSep 23, 2026

CETP

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…poprotein particles. This helps explain why the balance of HDL and other lipid particles is more complex than a single cholesterol number. Also called: Moving cholesterol between lipoproteins CETP transfers cholesteryl esters between lipop…

Gene referenceSep 23, 2026

CXCL13

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CXCL13 is a chemokine that attracts cells expressing CXCR5, including B cells. This pairing helps organize immune-cell traffic in lymphoid tissues and some chronic inflammatory settings. Also called: Guiding B cells to organized immune sit…

Gene referenceSep 23, 2026

CXCL8

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CXCL8 is the gene for IL-8, a chemokine involved in recruiting and activating neutrophils. IL-8 is the protein nickname; CXCL8 is the gene name a DNA report may use. Also called: IL-8: bringing neutrophils to the response CXCL8 is the gene…

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