TNF
Some search terms matchedTNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer.
Also called: Tumor Necrosis Fact…
Understanding a nutrient deficiency
Some search terms matchedHow the Purser approach moves from a nutrient finding to priorities, a manageable plan and reassessment.
Also called:
From a laboratory flag to a useful plan
Start with your original CMA report: check its date, values, and the lab’s catego…
Homocysteine and methylation
Some search terms matchedFollow Dr. Purser’s teaching on folate, B12, sulfur pathways and antioxidant support around homocysteine.
Also called:
Follow the branches around homocysteine
Homocysteine sits at a junction in the pathway. Dr. Purser’s teaching follows ho…
How to read a laboratory report
Some search terms matchedSeparate the gene, variant, measured value and clinical interpretation—and learn which questions to bring to your visit.
Also called:
Keep the original result in view
Start with your original report: check the date, units, the lab’s range,…
SLC19A1
Some search terms matchedEncodes the reduced folate carrier, a protein involved in transporting folates into cells.
Also called: RFC1, reduced folate carrier, folate transport
Folate transport is part of the story
Dr. Purser’s folate map includes transport as well …
ALPL
Some search terms matchedALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme important to bone and tooth mineralization and vitamin B6 metabolism. Persistently low alkaline phosphatase can deserve a different evaluation from a general nutrient deficienc…
CCL5
Some search terms matchedCCL5, also called RANTES, is a chemokine that helps direct immune-cell movement. Chemokines tell cells where to go, which is different from measuring the total strength of an immune response.
Also called:
RANTES and immune-cell recruitment…
CD40
Some search terms matchedCD40 encodes a receptor that participates in communication between immune cells, including T-cell help for B-cell responses. Its partner is CD40 ligand, encoded by CD40LG.
Also called:
A conversation between immune cells
CD40 encodes a rec…
CD40LG
Some search terms matchedCD40LG encodes CD40 ligand, which binds CD40 and supports communication needed for effective antibody responses. It is on the X chromosome, which changes how some genetic results must be interpreted.
Also called:
The ligand that helps acti…
CETP
Some search terms matched…poprotein particles. This helps explain why the balance of HDL and other lipid particles is more complex than a single cholesterol number.
Also called:
Moving cholesterol between lipoproteins
CETP transfers cholesteryl esters between lipop…
CXCL13
Some search terms matchedCXCL13 is a chemokine that attracts cells expressing CXCR5, including B cells. This pairing helps organize immune-cell traffic in lymphoid tissues and some chronic inflammatory settings.
Also called:
Guiding B cells to organized immune sit…
CXCL8
Some search terms matchedCXCL8 is the gene for IL-8, a chemokine involved in recruiting and activating neutrophils. IL-8 is the protein nickname; CXCL8 is the gene name a DNA report may use.
Also called:
IL-8: bringing neutrophils to the response
CXCL8 is the gene…
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