…d what is the underlying cause?
Variant IDs in the teaching reference: rs1800469, rs1800470, rs1800471
Also called: TGF-beta, TGF-β, Transforming growth factor beta 1
Where the VARS Triad and MTHFR Daily fit
If you are exploring homocystein…
…is its cause being established?
Variant IDs in the teaching reference: rs20575
Also called: DR4, Death receptor 4
Where the VARS Triad and MTHFR Daily fit
If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily an…
…issue injury in this situation?
Variant IDs in the teaching reference: rs1131568, rs4894559
Also called: TRAIL
Where the VARS Triad and MTHFR Daily fit
If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and t…
…bsorption, Intrinsic factor receptor activity, Methylation, Folate metabolism. These are topics to explore, not a diagnosis or a measurement of how the pathway works in your body.
Understanding a result
A gene name is only a starting point.…
… level is not just about what you eat.
Nutrition matters.
Folate matters.
Vitamin B12 matters.
Vitamin B6 matters.
Lifestyle matters.
Genetics may matter too.
So why are we waiting until disease appears before asking what our biology…
…r picture.
Variants such as C677T and A1298C can influence folate metabolism and methylation.
Stop blaming yourself.
Start understanding the biology.
Support your nutrition.
Support methylation when appropriate.
Prioritize protein,…
…d alongside kidney function, nutrition, genetics, and other laboratory findings.
Your lab results are more than numbers on a page.
They are clues that can help you ask better questions about your health.
Learn why kidney health and homoc…
…s can be more complicated than simply looking at a standard lab panel.
A CMA is designed to provide another perspective on how your cells respond to essential nutrients, giving you and your healthcare team additional information to conside…
…THFR gene variants (common in ~85% of people). These impair folate processing → elevated homocysteine → massive inflammation and cytokine storms (IL-6, TNF-α, IL-17, etc.).
High homocysteine (>10-12 µmol/L; ideal <7-8) acts like a "cytokin…
…R gene may be part of the reason. MTHFR (Methylenetetrahydrofolate Reductase) is a genetic SNP—a small DNA variation that affects how your body processes folate (vitamin B9).
The most common variants, C677T and A1298C, can reduce your abili…
Thyroid health remains essential during menopause. Optimal labs should show FT3 around 4.0 and FT4 near 1.5, and testing through Direct Labs makes it easy to track. Supporting with supplements like Thyromin can help, but only if guided by a…
…ome don’t matter, but others can throw off key systems like folate metabolism (MTHFR), antioxidant defense (SOD), and glutathione production.
While you can’t change your genes, you can support them. At Purser Wellness, we combine genetic an…
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