THE PURSER WELLNESS ENCYCLOPEDIA
4 chapters, at your pace
340 resources for your curiosity56 matching listings grouped; alternative sources stay available.
What’s searchable?This is a clip from https://danpursermd.substack.com/p/mthfr-and-the-never-ending-sugar?utm_source=youtube_shorts See the full video: https://www.youtube.com/watch?v=0BGJ_m5Cbrc #shorts #substack
Searchable captionsExplore dimethylarginine dimethylaminohydrolase 1 (DDAH1), asymmetric dimethylarginine (ADMA), nitric oxide, blood vessels, and related blood-vessel pathways.
What if the answers you've been searching for aren't found in another prescription—but inside your own cells? Most lab tests tell you what's circulating in your blood. But what if your cells are telling a different story? A Cellular Micro
What if everything you’ve been told about fatty liver is missing the real cause? It’s not just about diet, sugar, or alcohol. The deeper issue may lie in a little-known pathway most people have never heard of: PEMT. If that pathway isn’t wo
High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a blood test can measure homocysteine directly, while a CMA with Redox uncovers the vitamin deficiencies driving it. For genetic causes, the DRP Genetics panel screens 15–16 of the 17 known SNPs that can cause permanently high homocysteine. If your levels are fixed by genetics, reduced glutathione and targeted B vitamins (like MTHFR Daily) are key to balancing the
Searchable captionsRead matching passageThe real root of fibromyalgia? It’s not just pain — it’s copper. We’ve uncovered that fibromyalgia is often driven by genetic mutations (like CBS, GAD1, GAD2) that affect how your body handles copper. The copper builds up in your blood but never makes it into your cells — leading to widespread pain, inflammation, and migraines.
Searchable captionsRead matching passageHomocysteine is nasty — but here’s the truth no one tells you. It doesn’t kill you directly — it triggers white blood cells to release IL-8 and MCP-1, causing inflammation, kidney failure, heart attacks, and strokes. Most doctors don’t even check it anymore, thinking there’s no fix. But there is. Whether from 17 genetic SNPs or 12 vitamin deficiencies (like B6 or B12), you can address it by supporting your body’s ability to convert homocysteine into glutathione.
Searchable captionsRead matching passageStruggling with high blood pressure that just won’t budge—even with multiple meds? It might be due to genetic issues causing high homocysteine , which can stiffen your arteries through IL-8 and MCP-1 cytokines.
Did you know scurvy is still around today? It might sound like an old pirate disease, but a lack of Vitamin C can still cause fatigue, joint pain, bleeding gums, and slow healing. Without Vitamin C, your body can’t make collagen, which is essential for healthy skin, blood vessels, and connective tissues.
Superoxide Dismutase 3 (SOD 3), also known as extracellular SOD or ubiquitous SOD, plays a critical role in your body’s defense against inflammation and oxidative stress. Here’s why it matters: Stabilizes Mast Cells SOD 3 helps suppress mast cell activation, reducing the release of inflammatory mediators that contribute to conditions like skin inflammation, inflammatory bowel disease, and chronic pain. Reduces Pro-Inflammatory Cytokines By inhibiting cytokines like TNF-Alpha, SOD 3 can help soothe inflammation at its source. Supports Healthy Joints and Blood Vessels Whether you have joint disc
Scurvy, no one should have it in these modern ages, but I see these patients again and again. Thiamine Deficiency is another that NO ONE knows to look at, but it’s there. Remember, these are INTRACELLULAR deficiencies, not just blood serum levels. You have to Dig Deep to get the root of the issue.
High homocysteine levels can lead to inflammation, joint and muscle pain, and even shifting pain throughout the body. It’s also linked to birth defects and chronic kidney failure, and can raise blood pressure. Six genetic SNPs (like MTR, MTRR, and CBS) and MTHFR mutations (like C677T) can prevent homocysteine from converting into glutathione, which is essential for keeping inflammation in check. Plus, 12 vitamin deficiencies may temporarily raise homocysteine levels, so addressing these deficiencies is key.
Search looks for your words in titles, descriptions, available articles, learning guides, and video captions when available. The closest matches appear first. Duplicate posts are grouped, with links to other places you can read or watch them. Books, chapters, and reports have topic guides here; the original files and full book text are not available in this encyclopedia. Subscriber posts include a title and public summary; open Substack to read the full post.
