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YouTube·Website publication: Jan 6, 2026

Gene Types Explained

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By Andrew Behrman1 min read

Your genetic results might list “wild type,” “heterozygous,” or “homozygous,” but what does that mean? Wild type means both copies of your gene are normal, heterozygous means one is normal and one has a change, and homozygous means both copies have the same change. With genes like MTHFR, these variations can affect how efficiently your body processes nutrients like folate—sometimes cutting function by 40–70%—which is why targeted nutrition and testing matter.

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Original sourceDan Purser MD

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YouTube captions · May contain errors · Added Sep 23, 2026

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0:02

Hey, you just got your genetic results back and seeing stuff like wild type, hetererozygous, and homozygous for your MTHFR gene. We're getting real scientific here, aren't we? [music] Don't worry, I'm going to break it down for you. So, your MTHFR gene helps your body process folate, [music] a B vitamin that's super important for things like

0:18

making DNA, energy, and keeping your heart healthy. You've got two copies of this gene, one from your mom and one from your dad. The terms in your results in your genetic [music] results like wild type, hetererozygous or homozygous just tell you how those two copies are

0:34

set up. Especially when talking about mutations that have been passed [music] down called SNIPS like C677T and A1298C. Let's make it simple. First, [music] wild type or WT on your results. This means both your MTHFR gene copies are

0:50

the standard version most people have. It's like getting two regular cups of coffee. Nothing's changed. Your genes are doing its job converting folate into its active form. Basically, no [music] problem. Now, hetererozygous shows a plus and a minus. This means you've got

1:06

one normal MTHFR gene and one with a change like C677T or A1298C. It's like ordering one regular copy and one with a twist like get in decaf. For example, if you are hetererozygous for C677, your gene might work about 35 to

1:23

40% less efficiently. Usually, it could mean that you do need more folate from foods in your diet or with a nice supplement like MTHFR daily or other methylation support [music] product. Then there's homozygous, which is plus+ or minus minus. This means both your

1:41

MTHFR genes are the same, [music] either both normal or both with the same change, like two copies of the [music] C677T or A1298C. If it's the changed version, it's like doubling up on that decaf copy. For C677T, both copies being changed can cut

1:59

[music] your gene's efficiency by up to 70%. Which definitely leads to high homoyine [music] levels. A1298C homozygous is less intense, maybe a 40 to 50% drop, but still [music] definitely worth paying attention to. So, quick recap. [music] Wild type is

2:16

both of your genes as usual. Everything's working as it should. Hetererozygous is one normal gene and one changed. And then homozygous is both changed, which can make a big difference, especially with MTHFR, like you needing more folate or B12 or

2:32

glutathione to help things run smoothly. Your genetic results are a sneak peek into how your body [music] deals with all these different minerals, vitamins, and amino acids. How the enzymes in your body actually function. Knowing if you're wild type, hetererozygous or

2:47

homozygous for snips like MTHFR [music] or others can help you tweak your diet by eating the correct foods or working with our team to get you on the right supplements that you need. It's all about working [music] with your unique setup. Pretty cool, huh? If you have any

3:04

questions about your genetic testing, [music] your results, or what you need to do nutritionally to get going, reach out to our office. We are so happy to help.

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