DDAH1 | Purser Wellness Encyclopedia

THE TEACHING CONNECTION

Clearing ADMA helps preserve nitric oxide signaling

DDAH1 encodes an enzyme that breaks down asymmetric dimethylarginine, or ADMA. ADMA inhibits nitric oxide synthase; DDAH1 is part of its clearance system, not the inhibitor itself.

Putting the pieces together

Dr. Purser connects ADMA with homocysteine-related vascular and renal concerns. This gives a useful bridge from redox and homocysteine teaching to NOS3 and vessel function. The genotype does not measure ADMA concentration, kidney function or vascular damage.

Where the VARS Triad and MTHFR Daily fit

If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and the VARS Triad: VARS Glutathione, VARS SOD, and VARS Catalase. He gives glutathione a central place in his approach to antioxidant support.

A gene result alone cannot tell you that you need these products or that they will treat a condition. Review your current results, medicines, goals, and tolerance with your clinician before choosing a product or dose.

A question to bring to your visit

What do my kidney function, blood pressure and homocysteine measurements show?

Variant lookup

These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.

rs233112 rs480414 rs669173