… if you're homozygous means you can't make enough phosphotylcholine. It can cause you to have napp or fatty liver disease causes a nash then which go which is non-alcoholic stale hepatitis which means your liver is dying and getting really …
… B vitamin deficiency. It could be biotin even. It could be choline. Yeah, those are B vitamins. Um it could be a lot of other B vitamins. or it could be a vitamin C deficiency. Anyway, just giving you a heads up, take that and good vitamin…
… AHCY, CBS, and SUOX. Folate and B12 support remethylation; choline can provide betaine for the BHMT route. Transsulfuration connects homocysteine with cysteine and glutathione, and sulfur compounds pass through additional steps.
Bring the…
…Putting the pieces together
This connects the discussion to choline and betaine metabolism. It is a useful example of why Dr. Purser looks at several pathways together: the same laboratory marker can sit at the intersection of more than one…
…take and nutrients such as folate, B12, B6, riboflavin, and choline can affect different parts of this pathway. That is why your food history and other tests matter along with a homocysteine number.
A low result does not prove a hidden def…
…help with one recycling route. Betaine, which can come from choline, helps with another. CBS and CTH carry out the two core steps toward cysteine. These nutrients and enzymes work together, but they do different jobs.
How Dr. Purser connect…
…methylation, and the relationship between folate demand and choline. Choline can also support the betaine/BHMT route and phosphatidylcholine production.
Bring these questions to your visit
Ask whether folate, B12, homocysteine, choline int…
…s an important role in the body's production of phosphatidylcholine, which is involved in transporting fat out of the liver. Certain genetic variations may influence this pathway and can affect individual choline requirements.
So what if u…
…ons in the PEMT gene. This pathway plays a critical role in choline metabolism and the body's ability to move fat out of the liver. When it isn't functioning optimally, fat can accumulate even in people who are doing "everything right."
Th…
…T defects (common co-driver of SIBO, NAFLD, IBD) → targeted choline and phosphatidylcholine. Step 3: Monitor & Titrate Retest homocysteine and cytokines at 8–12 weeks. I have watched IL-6 drop 60–80% and patients come off biologics. Step 4:…
…culprit! This gene controls how your body makes phosphatidylcholine (PC)—a vital fat for liver function, bile production, and gut health.
What is PEMT & Why Does It Matter?
The PEMT enzyme helps your liver make phosphatidylcholine (PC), wh…
…ents can address prevalent health issues:
Hair Loss: Zinc, choline, and biotin are essential for healthy hair growth and strength. These nutrients support hair follicles and could prevent hair loss.
Memory Loss: Enhancing memory requires …
Search looks for your words in titles, descriptions, available articles, learning guides, and video captions when available. The closest matches appear first. Duplicate posts are grouped, with links to other places you can read or watch them. Books, chapters, and reports have topic guides here; the original files and full book text are not available in this encyclopedia. Subscriber posts include a title and public summary; open Substack to read the full post.