THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “Homocysteine, folate transport, and uric acid”

Explore this topic as a step-by-step interactive map.MTHFR, the citric acid cycle & ATP
A RELATED COURSEMethylation & B vitamins

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YouTubeFeb 15, 2026

Why does MTHFR correlate with high homocysteine?

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Follow Dr. Purser! Did you know your MTHFR gene can impact your homocysteine levels? High homocysteine is linked to heart and brain health—understanding this connection could be the key to solving your mystery medical problems that no doctor or study has been able to figure out. Curious how it all works? Let’s break it down in simple terms. #insulin #genetics #vitamins #Vars #wellness #PEMT #inflammation #glutathione #MicronutrientTesting #FunctionalMedicine #SOD #Homocysteine #ChronicInflammation #MethylationMatters #FunctionalWellness #GeneticTesting #NutrientDeficiency #MTHFR #fibromyalgia #Methylation #DrDanPurser #purserwellness Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

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YouTubeSep 30, 2025

TMG A Viable Option For Homocysteine?

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TMG (trimethylglycine) can sometimes lower homocysteine—but only if it’s not caused by genetics. When homocysteine is high from genetic SNPs, TMG won’t fix it, and restrictive “low-methionine diets” are both harmful and outdated. The real solution lies in addressing deficiencies and genetics directly. Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

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YouTubeAug 29, 2025

Is Your Fibromyalgia Affected by High Homocysteine?

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🧬 High homocysteine isn’t just a heart problem—it’s a major player in fibromyalgia. If you’ve got fibro symptoms, there’s a good chance your transsulfuration pathway is broken—often due to 17 different SNPs or 12 key nutrient deficiencies. That means your body can’t detox properly or convert homocysteine into glutathione, leading to inflammation, pain, and fatigue. Don’t just chase labs—fix the root cause. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

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Health BlogMar 13, 2026

The Hidden Molecule Driving Inflammation: Understanding the Purser Model of Homocysteine

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Most people have never heard of homocysteine , yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model , which explains why ho

Gene referenceSep 23, 2026

FOLR1

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FOLR1 encodes folate receptor alpha, which helps cells take up folate and has an important role in folate transport at the brain’s barriers. Blood folate and folate availability in the nervous system are not identical measurements.

FacebookSep 15, 2026

Homocysteine rarely gets the attention of cholesterol, blood sugar, or blood pressure.

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Homocysteine rarely gets the attention of cholesterol, blood sugar, or blood pressure. It should. When homocysteine becomes elevated, it has been associated with cardiovascular disease, stroke, cognitive decline, blood clots, and other he

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YouTubeMay 30, 2026

Autism Answered - Root Cause Solved with #1 Reviewed MD in the USA

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Hi, I’m Dr. Dan Purser. For too long, autism has been treated as a mystery with only symptom management. In this episode, I break down what I’ve seen consistently in practice: the real root cause behind many cases on the spectrum. It starts with genetic variants (especially MTHFR and related SNPs) that break the transsulfuration pathway. When kids can’t efficiently convert homocysteine into glutathione, they lose their ability to detox heavy metals and environmental toxins. The result is chronic inflammation, oxidative stress, and developmental challenges. The good news? Once we identify these biochemical and genetic imbalances through proper testing, we can intervene at the root with targeted support — restoring methylation, rebuilding glutathione function, and giving the body what it needs to heal. This isn’t theory. It’s the Purser Method® in action. If you’re a parent searching for real answers instead of just labels, this episode is for you. The root cause has been solved. Now let’s talk solutions.

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FacebookMay 1, 2026

🧬 MTHFR Mutations, High Homocysteine & Autoimmune Disease: The Hidden Root Cause Most Doctors Miss

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🧬 MTHFR Mutations, High Homocysteine & Autoimmune Disease: The Hidden Root Cause Most Doctors Miss For decades, patients with RA, lupus, MS, Hashimoto’s, and fibromyalgia chase symptom relief with meds that never fix the underlying fire. A

InstagramNov 6, 2025

Every woman with PCOS I’ve ever tested has a homocysteine problem...

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Every woman with PCOS I’ve ever tested has a homocysteine problem... That’s what Dr. Dan Purser says — and it might explain why so many women with PCOS struggle with pain, inflammation, fatigue, and even kidney or blood pressure issues. Hom

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InstagramNov 6, 2024

Ever wondered how Homocysteine, MTHFR, and Glutathione are connected? Homocysteine is a highly inflammatory…

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Ever wondered how Homocysteine, MTHFR, and Glutathione are connected? Homocysteine is a highly inflammatory substance that triggers cytokine release in the body, fueling inflammation. It’s part of the methionine cycle, which links directly

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FacebookDec 21, 2023

Folic Acid, is it toxic? Gary Brecka syas yes, but inly in 44% of the population. What about the rest? We have…

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Folic Acid, is it toxic? Gary Brecka syas yes, but inly in 44% of the population. What about the rest? We have receptors for Folic Acid on our cells, but some have geneitc deficiencies that dont allow them to process it. Some, but not all. …

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