Let’s explore “IL-10 & promoter variants”

F9 encodes coagulation factor IX. Disease-causing variants can result in hemophilia B, an inherited bleeding disorder, but a panel marker is not equivalent to a confirmed disease-causing finding.

Explore rs2857261, rs1057972, natural killer cells, CD8+ T cells, and questions about high-expression variants.

Explore HbA1c, red blood cell turnover, hemoglobin variants, blood loss, hypoglycemia, and factors that may affect a low A1C result.

You eat something sweet. Your energy shoots up. Then suddenly you are exhausted, foggy, irritable, and reaching for something else to get you through the day. That cycle deserves a closer look. MTHFR variants can influence folate meta

Explore transsulfuration, methylation, glutathione, genetic variants, cytokines, and possible connections.

Explore the IFNG promoter variant rs2069705, the -1616 position, STAT4, and questions about interferon-gamma regulation.

Explore Th17 cells, mucosal immunity, the rs2275913 promoter variant, and inflammatory conditions.

What if the biggest breakthroughs in autism support aren’t coming from symptom management alone? In our latest article, we dive deep into what we’ve seen consistently in practice: how genetic variants (especially MTHFR and related SNPs) ca

PURSER WELLNESSAutism Answered - Root Cause Solved with #1 Reviewed MD in the USAA conversation with Dr. Purser

Hi, I’m Dr. Dan Purser. For too long, autism has been treated as a mystery with only symptom management. In this episode, I break down what I’ve seen consistently in practice: the real root cause behind many cases on the spectrum. It starts with genetic variants (especially MTHFR and related SNPs) that break the transsulfuration pathway. When kids can’t efficiently convert homocysteine into glutathione, they lose their ability to detox heavy metals and environmental toxins. The result is chronic inflammation, oxidative stress, and developmental challenges. The good news? Once we identify these biochemical and genetic imbalances through proper testing, we can intervene at the root with targeted support — restoring methylation, rebuilding glutathione function, and giving the body what it needs to heal. This isn’t theory. It’s the Purser Method® in action. If you’re a parent searching for real answers instead of just labels, this episode is for you. The root cause has been solved. Now let’s talk solutions.

PURSER WELLNESSWhat is MTHFR? What can YOU do about it?A conversation with Dr. Purser

MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialized folates, B12 forms, and glutathione can bypass the blockages, and products like MTHFR Daily were designed specifically to fill these nutrient gaps so patients can restore energy and thrive.

Glutathione is called the “master antioxidant” because it protects every cell in your body from oxidative damage, supports detox, and reduces inflammation. People with high homocysteine or MTHFR gene variants often can’t recycle glutathione

Feeling exhausted and super sensitive to supplements? 😩 You might think it’s adrenal fatigue, but in many cases, it’s actually due to vitamin deficiencies—especially in those with MTHFR or FOLR2 gene mutations. These genetic variants can im