THE PURSER WELLNESS ENCYCLOPEDIA

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Health BlogMar 13, 2026

The Hidden Molecule Driving Inflammation: Understanding the Purser Model of Homocysteine

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Most people have never heard of homocysteine , yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a tox…

Nutrient referenceSep 23, 2026

Iron

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Helps hemoglobin carry oxygen and supports many cellular processes. Also called: Iron Energy is not enough reason to add iron Dr. Purser’s course connects iron with oxygen transport and energy while identifying it as a safety-sensitive mine…

Gene referenceSep 23, 2026

APOE

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APOE encodes a protein that carries lipids between cells. The familiar APOE e2, e3 and e4 groupings depend on the combination of rs429358 and rs7412, not on either marker read in isolation. Also called: Apolipoprotein E Lipid transport and …

Gene referenceSep 23, 2026

CBS

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CBS helps move homocysteine into the pathway that supplies building blocks for glutathione. Also called: Cystathionine Beta-Synthase From homocysteine toward glutathione Dr. Purser places CBS in the sulfur-handling pathway that connects hom…

Gene referenceSep 23, 2026

COL5A1

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COL5A1 encodes one component of type V collagen, which helps organize collagen fibers. It connects to the strength and structure of tendons, skin and other connective tissues. Also called: Collagen Type V Alpha 1 Chain Collagen structure, t…

Gene referenceSep 23, 2026

CTH

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CTH helps make cysteine, one of the building blocks your body uses to make glutathione. Also called: Cystathionine Gamma-Lyase From homocysteine toward glutathione Dr. Purser places CTH in the sulfur-handling pathway that connects homocyste…

Gene referenceSep 23, 2026

TNF

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TNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer. Also called: Tumor Necrosis Fact…

Gene referenceSep 23, 2026

IL4

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IL4 encodes interleukin-4, a cytokine involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself. Also calle…

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