SHBG
Some search terms matched…nd family history matter. Many common variants do not cause disease.
Nutrients and next steps
A genetic finding cannot show a nutrient deficiency or tell you how much of a supplement to take. Bring the original report to your clinician and …
SULT1A1
Some search terms matchedSULT1A1 is the gene name for Sulfotransferase 1A1. Learn what a specific result could mean and what to ask about it.
Also called: Sulfotransferase 1A1
Start here
SULT1A1 is the gene name for Sulfotransferase 1A1. Learn what a specific resul…
TPSAB1
Some search terms matchedTPSAB1 is the gene name for Alpha Tryptase. Learn what a specific result could mean and what to ask about it.
Also called: Alpha Tryptase
Start here
TPSAB1 is the gene name for Alpha Tryptase. Learn what a specific result could mean and wha…
HFE (H63D / rs1799945) & iron
Some search terms matchedExplore HFE, H63D, rs1799945, C282Y, hereditary hemochromatosis, iron overload, ferritin, transferrin saturation, and monitoring and phlebotomy.
Understand the connection
HFE helps regulate iron absorption. H63D, identified as rs1799945, i…
IL-23R & liver health
Some search terms matchedExplore NAFLD, NASH, MASLD, MASH, hepatitis, the IL-23/IL-17 axis, and liver inflammation.
Understand the connection
Dr. Purser explores IL-23 and Th17 signaling in fatty liver disease and inflammatory liver conditions. Older terms NAFLD a…
IL-6 & liver health
Some search terms matched…tance, and inflammatory responses in the liver. Fatty liver disease can progress to inflammation and scarring in some people.
Follow the pathway
Dr. Purser discusses hepatic stellate cells, fibrosis, and the interaction of cytokines with r…
Low hemoglobin A1C: interpreting the result
Some search terms matchedExplore HbA1c, red blood cell turnover, hemoglobin variants, blood loss, hypoglycemia, and factors that may affect a low A1C result.
Understand the connection
A1C reflects glucose attached to red blood cells over time. A low result can ind…
Multiple sclerosis & cytokines
Some search terms matched…h the diagnosis.
Follow the pathway
Dr. Purser discusses Th1 and Th17 cells, TNF-alpha, IL-6, IL-17, and oxidative stress around active lesions. He connects this with the blood–brain barrier and the energy demands of affected cells while s…
MTHFD1 & one-carbon metabolism
Some search terms matchedExplore rs2236225, rs1076991, folate-dependent one-carbon metabolism, nucleotide synthesis, homocysteine, and double homozygosity.
Understand the connection
MTHFD1 helps interconvert forms of folate used in one-carbon metabolism. These rea…
CCL5 / RANTES
Some search terms matched…ANTES, attracts immune cells through receptors including CCR1, CCR3, and CCR5. It participates in the normal response to infection and tissue injury.
Follow the pathway
Dr. Purser discusses CCL5 in chronic inflammatory and immune condition…
IFNG rs2069705
Some search terms matchedExplore the IFNG promoter variant rs2069705, the -1616 position, STAT4, and questions about interferon-gamma regulation.
Understand the connection
IFNG rs2069705 is a genetic identifier discussed in connection with interferon-gamma regulat…
IL-17A rs2275913
Some search terms matchedExplore Th17 cells, mucosal immunity, the rs2275913 promoter variant, and inflammatory conditions.
Understand the connection
IL-17A is part of the Th17 immune pathway and helps organize responses at barrier tissues. It can stimulate other …
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