…the body’s antioxidant defenses.
Also called: Superoxide Dismutase 3
Superoxide defense in its own setting
Dr. Purser teaches SOD as one member of an antioxidant team. SOD3 works outside cells and uses copper and zinc. SOD converts superoxi…
TCN2 helps carry vitamin B12 in the body. A gene result alone cannot tell you your B12 status.
Also called: Transcobalamin II
B12 must be carried as well as consumed
TCN2 appears in Dr. Purser’s homocysteine and methylation map because it c…
TNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer.
Also called: Tumor Necrosis Fact…
VDR encodes the vitamin D receptor, which helps regulate gene activity in response to active vitamin D. A receptor variant does not by itself mean receptors are absent or that the blood vitamin D level is low.
Also called: Vitamin D Recepto…
VKORC1 encodes vitamin K epoxide reductase, part of the vitamin K recycling system used in activating clotting proteins. It is not simply a vitamin K receptor.
Also called: Vitamin K Epoxide Reductase Complex Subunit 1
Recycling vitamin K a…
How the Purser approach moves from a nutrient finding to priorities, a manageable plan and reassessment.
Also called:
From a laboratory flag to a useful plan
Start with your original CMA report: check its date, values, and the lab’s catego…
…late, B12, sulfur pathways and antioxidant support around homocysteine.
Also called:
Follow the branches around homocysteine
Homocysteine sits at a junction in the pathway. Dr. Purser’s teaching follows homocysteine in two directions: reme…
Separate the gene, variant, measured value and clinical interpretation—and learn which questions to bring to your visit.
Also called:
Keep the original result in view
Start with your original report: check the date, units, the lab’s range,…
…t
Folate transport is part of the story
Dr. Purser’s folate map includes transport as well as conversion. SLC19A1 is a folate transporter, so its teaching role differs from MTHFR: getting folate into cells is a separate step from changing i…
…LPL encodes tissue-nonspecific alkaline phosphatase, an enzyme important to bone and tooth mineralization and vitamin B6 metabolism. Persistently low alkaline phosphatase can deserve a different evaluation from a general nutrient deficiency…
CCL11 encodes eotaxin-1, a chemokine best known for attracting eosinophils. Its receptor relationships connect it to allergic inflammation as well as broader research into immune signaling.
Also called:
Eotaxin-1 and eosinophil recruitment…
CCL2 encodes MCP-1, a chemokine that attracts monocytes toward sites of immune activity. Recruitment is a different task from the cytokines that activate those cells once they arrive.
Also called:
MCP-1: recruiting monocytes
CCL2 encodes M…
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