IL4
Some search terms matchedIL4 encodes interleukin-4, a cytokine involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself.
Also calle…
IL5
Some search terms matchedIL5 encodes interleukin-5, a cytokine important to eosinophil growth, survival and activation. Eosinophils are involved in selected allergic and other inflammatory conditions.
Also called:
An eosinophil-focused cytokine
IL5 encodes interle…
IL6R
Some search terms matchedIL6R encodes the interleukin-6 receptor. Membrane-bound and soluble receptor pathways help explain why IL-6 biology involves more than the amount of cytokine in a single blood sample.
Also called:
Receiving and relaying the IL-6 signal
IL6…
MTHFS
Some search terms matchedMTHFS encodes an enzyme that converts 5-formyltetrahydrofolate into 5,10-methenyltetrahydrofolate. This places it in folate interconversion; it is not another name for MTHFR or a direct maker of methylfolate.
Also called:
Folinic acid has …
TGFB1
Some search terms matchedTGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effects can include both regulation of inflammation and promotion of fibrosis.
Also called:
Repai…
TNFRSF10A
Some search terms matchedTNFRSF10A encodes death receptor 4, or DR4, a receptor that can receive the TRAIL signal and participate in regulated cell-death pathways. TRAIL itself is encoded by TNFSF10.
Also called:
DR4 receives the TRAIL signal
TNFRSF10A encodes dea…
GABPA
Some search terms matchedGABPA is a gene involved in controlling how other genes are used. You may see the label GABP1 in older materials; check the exact variant on your own report.
Also called: GABP1, GA Binding Protein Transcription Factor Subunit Alpha
Start he…
IL-15 & homozygosity
Some search terms matchedExplore rs2857261, rs1057972, natural killer cells, CD8+ T cells, and questions about high-expression variants.
Understand the connection
IL-15 supports natural killer cells and certain T cells, including memory CD8+ T cells. Immune memory…
IL-23R & liver health
Some search terms matched…e IL-23/IL-17 axis, and liver inflammation.
Understand the connection
Dr. Purser explores IL-23 and Th17 signaling in fatty liver disease and inflammatory liver conditions. Older terms NAFLD and NASH appear alongside the newer terms MASLD …
IL-6 & migraines
Some search terms matchedExplore migraine, neurovascular inflammation, trigeminal signaling, CGRP, and related research.
Understand the connection
Migraines involve nervous-system signaling and can include inflammatory processes. Dr. Purser discusses IL-6 as one s…
Telogen effluvium & nutrient discussions
Some search terms matchedExplore hair shedding, the hair-growth cycle, telogen effluvium, nutrient deficiencies, and questions about changes during supplementation.
Understand the connection
Telogen effluvium is a pattern of hair shedding that can follow illness, …
TNF-alpha
Some search terms matchedExplore tumor necrosis factor-alpha, TNFR1, TNFR2, rs1800629, inflammatory signaling, and treatment comparisons in Purser Wellness teaching.
Understand the connection
TNF-alpha is an immune messenger involved in defense, inflammation, and …
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