Let’s explore “2-hour glucose, 75 g OGTT — lab reference”

PSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis. Also called:…

SERPINE1 makes PAI-1, a protein involved in breaking down blood clots. You may also see PAI4G used for this pathway. Also called: PAI-1, PAI4G, Plasminogen Activator Inhibitor-1, Plasminogen Activator Inhibitor 1, 4G/5G Polymorphism Balanci…

SHMT1 connects serine and glycine with folate chemistry. Also called: Serine Hydroxymethyltransferase 1 Where amino acids meet folate SHMT1 connects serine and glycine with folate pathways. That is one reason both nutrition and genetics can…

… Superoxide Dismutase 1 Superoxide defense in its own setting Dr. Purser teaches SOD as one member of an antioxidant team. SOD1 works primarily inside cells and uses copper and zinc. SOD converts superoxide into hydrogen peroxide, which exp…

… Superoxide Dismutase 3 Superoxide defense in its own setting Dr. Purser teaches SOD as one member of an antioxidant team. SOD3 works outside cells and uses copper and zinc. SOD converts superoxide into hydrogen peroxide, which explains the…

TCN2 helps carry vitamin B12 in the body. A gene result alone cannot tell you your B12 status. Also called: Transcobalamin II B12 must be carried as well as consumed TCN2 appears in Dr. Purser’s homocysteine and methylation map because it c…

TNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer. Also called: Tumor Necrosis Fact…

VDR encodes the vitamin D receptor, which helps regulate gene activity in response to active vitamin D. A receptor variant does not by itself mean receptors are absent or that the blood vitamin D level is low. Also called: Vitamin D Recepto…

… vitamin K epoxide reductase, part of the vitamin K recycling system used in activating clotting proteins. It is not simply a vitamin K receptor. Also called: Vitamin K Epoxide Reductase Complex Subunit 1 Recycling vitamin K and responding …

How the Purser approach moves from a nutrient finding to priorities, a manageable plan and reassessment. Also called: From a laboratory flag to a useful plan Start with your original CMA report: check its date, values, and the lab’s catego…

Follow Dr. Purser’s teaching on folate, B12, sulfur pathways and antioxidant support around homocysteine. Also called: Follow the branches around homocysteine Homocysteine sits at a junction in the pathway. Dr. Purser’s teaching follows ho…

Separate the gene, variant, measured value and clinical interpretation—and learn which questions to bring to your visit. Also called: Keep the original result in view Start with your original report: check the date, units, the lab’s range,…