RAD50 encodes a DNA-repair protein. The surrounding genomic region also contains regulatory elements relevant to the nearby IL4, IL5 and IL13 cluster, so a locus association can concern more than the coding function of one gene.
Also called…
TGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effects can include both regulation of inflammation and promotion of fibrosis.
Also called:
Repai…
…receptor 4, or DR4, a receptor that can receive the TRAIL signal and participate in regulated cell-death pathways. TRAIL itself is encoded by TNFSF10.
Also called:
DR4 receives the TRAIL signal
TNFRSF10A encodes death receptor 4, or DR4, a…
TNFSF10 encodes TRAIL, a signaling protein involved in regulated cell death through particular receptors. It is a different member of the TNF-related signaling family from TNF itself.
Also called:
TRAIL and regulated cell death
TNFSF10 enc…
See how homocysteine connects to cysteine and glutathione. Follow seven simple steps, explore the side routes, and tap a word or building block to learn more.
Also called: Transsulfuration, Transsulphuration, Sulfur pathway, Cysteine synthe…
FOLR3 is the gene name for Folate Receptor 3. Learn what a specific result could mean and what to ask about it.
Also called: Folate Receptor 3
Start here
FOLR3 is the gene name for Folate Receptor 3. Learn what a specific result could mean …
Explore HbA1c, red blood cell turnover, hemoglobin variants, blood loss, hypoglycemia, and factors that may affect a low A1C result.
Understand the connection
A1C reflects glucose attached to red blood cells over time. A low result can ind…
What if your constant sugar cravings are not simply a willpower problem?
You wake up tired.
You reach for sugar or quick carbohydrates.
You feel better for a little while.
Then the crash hits and you are searching for energy all over ag…
…
Understand the connection
CD14 helps the immune system recognize lipopolysaccharide, or LPS, from the outer surface of certain bacteria. It appears on cell surfaces and also circulates as soluble CD14.
Follow the pathway
Dr. Purser explai…
Explore rs1800925, rs20541, IL-13 receptor terminology, and biologic and antioxidant approaches.
Understand the connection
IL-13 participates in type 2 immune signaling, including mucus production, allergic inflammation, and changes in bar…
Explore interleukin-4, Th2 cells, immunoglobulin E (IgE), and allergic and atopic conditions.
Understand the connection
IL-4 helps organize type 2 immune responses and supports antibody switching toward IgE. This makes it relevant to aller…
What if your homocysteine level is telling you more than you realize?
When kidney function declines, homocysteine levels often rise because the kidneys play an important role in its metabolism and clearance. In people with chronic kidney d…
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