THE PURSER WELLNESS ENCYCLOPEDIA

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Gene referenceSep 23, 2026

CBS

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CBS helps move homocysteine into the pathway that supplies building blocks for glutathione. Also called: Cystathionine Beta-Synthase From homocysteine toward glutathione Dr. Purser places CBS in the sulfur-handling pathway that connects hom…

Gene referenceSep 23, 2026

CD14

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CD14 helps immune cells recognize microbial components, including bacterial lipopolysaccharide, as part of innate immune signaling. This places it upstream of some cytokine responses. Also called: Cluster of Differentiation 14 How immune ce…

Gene referenceSep 23, 2026

CHDH

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CHDH helps convert choline toward betaine, a nutrient involved in the homocysteine pathway. Also called: Choline Dehydrogenase Choline can serve more than one purpose CHDH helps convert choline toward betaine, while PEMT helps make phosphat…

Gene referenceSep 23, 2026

COL5A1

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COL5A1 encodes one component of type V collagen, which helps organize collagen fibers. It connects to the strength and structure of tendons, skin and other connective tissues. Also called: Collagen Type V Alpha 1 Chain Collagen structure, t…

Gene referenceSep 23, 2026

COMT

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Makes an enzyme that helps break down catechol compounds, including some neurotransmitters. A common variant does not by itself explain mood, attention or stress tolerance. Also called: Catechol-O-Methyltransferase Catecholamines and sensit…

Gene referenceSep 23, 2026

CTH

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CTH helps make cysteine, one of the building blocks your body uses to make glutathione. Also called: Cystathionine Gamma-Lyase From homocysteine toward glutathione Dr. Purser places CTH in the sulfur-handling pathway that connects homocyste…

Gene referenceSep 23, 2026

FADS1

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Encodes an enzyme involved in fatty-acid metabolism. Also called: Fatty Acid Desaturase 1 / D5D The form of a fatty acid matters Dr. Purser teaches FADS genes as a conversion pathway. FADS1 participates in a delta-5 desaturase step in fatty…

Gene referenceSep 23, 2026

FADS2

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Encodes an enzyme involved in fatty-acid metabolism. Also called: Fatty Acid Desaturase 2 / D6D The form of a fatty acid matters Dr. Purser teaches FADS genes as a conversion pathway. FADS2 participates in a delta-6 desaturase step in fatty…

Gene referenceSep 23, 2026

G6PC2

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G6PC2 encodes a glucose-6-phosphatase-related protein expressed in pancreatic islet cells. Common variation is associated with differences in fasting glucose regulation; it is not the insulin receptor. Also called: Glucose-6-Phosphatase Cat…

Gene referenceSep 23, 2026

GAD2

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GAD2 helps make GABA, a chemical messenger, from glutamate. Also called: Glutamate Decarboxylase 2 Another part of the GABA system GAD2 helps make GABA from glutamate. GAD1 does a related job, but the two genes are different. Check the exac…

Gene referenceSep 23, 2026

GCLC

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GCLC helps make glutathione, an antioxidant your body produces. Also called: Glutamate-Cysteine Ligase Catalytic Subunit Making glutathione is a process Dr. Purser groups GCLC and GCLM as glutathione-synthesis machinery. GCLC supplies the c…

Gene referenceSep 23, 2026

GCLM

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GCLM helps regulate one of the steps your body uses to make glutathione. Also called: Glutamate-Cysteine Ligase Modifier Subunit Making glutathione is a process Dr. Purser groups GCLC and GCLM as glutathione-synthesis machinery. GCLM suppli…

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