Let’s explore “BRCA1, BRCA2, and common variants”

Learn why a common SNP and a pathogenic BRCA variant are different findings.

BRCA1 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding.

BRCA2 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding.

Classify by evidence, zygosity, phenotype, and clinical actionability rather than a numeric range.

High homocysteine levels are a common issue, often linked to genetics. There are seven gene variants (like MTHFR, CBS, and others) that can make it tough to bring those levels down. If you're dealing with this, the key is to look at your IL

Explore rs1801406, BRCA2, DNA repair, cancer-risk interpretation, genetic counseling, and inflammatory signaling; your exact result needs a clinician’s interpretation.

FTO is studied in relation to body weight and energy balance. Common variants can contribute to population-level differences in obesity susceptibility, alongside many other genes and environmental factors.

Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.

PSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.

PSEN2 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.

MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health. While they don’t directly cause blood sugar crashes, understanding your genetics, nutrition, sleep, stress, and nutrient status c

Explore monoamine oxidase, the MAOA and MAOB genes, rs1137070, rs2072743, rs66323, rs1799836, rs2283729, neurotransmitter metabolism, dietary amines, and treatment research.