ADRENAL FATIGUE.
This is being mentioned and discussed in the fibromyalgia forum and it's been something I needed to cover. So hang on and don't lose your collective minds over this but it's not really a medical diagnosis or actual endocri
In this consultation review, Jackson sat down with longtime Purser Wellness patient Lois Schweigert to go over her latest intracellular micronutrient (CMA) test results.
After years of dealing with fibromyalgia, pain, gut issues, and inconsistent energy, Lois has made remarkable progress. Her newest CMA shows ZERO deficiencies — her best results ever — and it perfectly matches how great she’s been feeling.
We discuss:
• Her consistent weight training and dramatically improved recovery (thanks to catalase!)
• Key optimization tweaks: amino acids, omega-3s, chromium, inositol, and glutathione
• Blood sugar stability
• Sleep support and overnight recovery
• How trauma & stress affect your nutrient levels
• Why intracellular testing is so unique and powerful
If you’re dealing with chronic symptoms, poor workout recovery, or just want to optimize your health, this conversation is packed with practical insights from real patient results.
👉 Ready to get your own CMA? Visit danpursermd.com or comment “CMA” below and we’ll send you info.
#PurserWellness #Fibromyalgia #RootCauseHealth #CMATest #FunctionalMedicine
This video is for educational purposes only and is based on Dr. Dan Purser’s protocols. Not medical advice. Always consult with your healthcare provider.
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CXCL13 is a chemokine that attracts cells expressing CXCR5, including B cells. This pairing helps organize immune-cell traffic in lymphoid tissues and some chronic inflammatory settings.
What if your homocysteine level is telling you more than you realize?
When kidney function declines, homocysteine levels often rise because the kidneys play an important role in its metabolism and clearance. In people with chronic kidney d
Can the B vitamins you are taking to support energy and methylation eventually make you feel worse?
In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as:
• 5-MTHF or methylfolate
• Methylcobalamin
• Trimethylglycine, also called TMG
• Multiple overlapping methylation formulas
Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.”
These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered.
In this video, we discuss:
• Why methylation is essential
• How methyl-donor supplements support the body
• Why the right vitamin can become the wrong dose
• Ingredients to look for on your supplement labels
• Why some people may need lower doses or non-methylated forms
• How genetics and intracellular nutrient testing can guide a more personalized plan
At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual.
Learn more or schedule with Purser Wellness:
https://danpursermd.com
Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional.
#Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness
Follow Dr. Purser!
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
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Feeling tired all the time is often dismissed as stress, aging, or a busy schedule.
But persistent fatigue can have many possible causes, including nutritional issues that may not be obvious from routine testing.
A Cellular Micronutrient
What if your recovery routine is just as important as your workout?
Sore muscles, lingering fatigue, and slow recovery can make it harder to stay consistent in the gym.
But what if supporting your body's recovery could help you get back
MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets
If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.”
In this video, we break down exactly why this happens:
How MTHFR/methylation issues impair ATP (energy) production at the cellular level
Why your body desperately reaches for quick glucose
The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage
The downstream effects on antioxidants, DNA repair, and overall energy
How to finally break the cycle:
Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests)
Why our MTHFR Daily multivitamin was specifically formulated for this
The power of CMA intracellular testing
Intermittent fasting (12–16 hrs)
Fasted cardio (even just a brisk walk)
High-protein, real-food diet with minimal processed sugars
If you’re tired of the sugar rollercoaster and want stable energy, this is for you.
Links:
Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle
Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com
Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily
Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious!
#MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting
Follow Dr. Purser!
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
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🔬 What is VARS? Why the VARS Trio (Glutathione + SOD + Catalase) is a game-changer for inflammation, recovery & fibromyalgia.
Jackson Larkin sits down with Lois Schweiger to break down Dr. Dan Purser MD’s VARS line — Validated, Absorbable, Reduced, and Stable antioxidants. Learn the science behind VARS Glutathione, VARS SOD (from deep-sea algae near volcanic vents), and the newest VARS Catalase (Nrf2 activator from seaweed).
Discover:
• How the VARS Triad works together in the mitochondria to fight oxidative stress and cytokines
• Why Catalase dramatically improved post-workout recovery (especially leg day!)
• Genetics, homocysteine, PEMT, and why many with fibro benefit from this protocol
• The importance of CMA (intracellular) testing and when to retest
• Real patient results, including severe inflammation cases
Perfect for anyone dealing with chronic pain, inflammation, slow recovery, or looking for root-cause support.
**June Anniversary Special**: $100 off Genetic + CMA testing — one order will be fully reimbursed!
👉 Learn more & shop VARS supplements: danpursermd.com
#VARSGlutathione #Fibromyalgia #Antioxidants #ChronicInflammation #PurserWellness #Catalase #SOD
Timestamps:
00:00 Intro & What Does VARS Mean?
01:45 The Science of the VARS Triad
12:00 Who Needs the Trio?
14:00 Catalase & Workout Recovery Stories
20:00 Genetics, Homocysteine & Testing
Follow Dr. Purser!
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
Twitter: https://twitter.com/realdanpursermd
YouTube: https://www.youtube.com/danpursermd
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Dan Purser MD interviews a patient with a brutal sarcoidosis case involving sky-high SIL2R cytokines, GI sarcoid, heart damage, and years of being dismissed by doctors. After spleen removal, repeated ER visits, and nitroglycerin dependence, he finally found answers.
Learn how cytokine testing and the VARS Trio (Glutathione + SOD + Catalase) led to rapid improvement — going from bedridden fear to playing with grandkids in just weeks.
This episode highlights the power of root-cause medicine for complex inflammatory conditions and offers hope for those who feel lost in the system.
Perfect for listeners dealing with sarcoidosis, chronic inflammation, autoimmune issues, or cytokine-related symptoms.
#Sarcoidosis #Cytokines #VARS #PurserWellness #ChronicIllnessRecovery
Follow Dr. Purser!
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
Twitter: https://twitter.com/realdanpursermd
YouTube: https://www.youtube.com/danpursermd
Instagram: https://www.instagram.com/danpurser.md
Pinterest: https://www.pinterest.com/danpursermd
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