Let’s explore “Homocysteine, folate transport, and uric acid”

PURSER WELLNESSAUTSIM - What is a potential ROOT CAUSE of Autism? Can it be helped?A conversation with Dr. Purser

What I see again and again is an inability to detox caused by failures in the Transsulfuration Pathway. This is your pathway that converts homocysteine to glutathione. If you have MTHFR or 16 other Gene SNPs, you will have problems with this pathway.

PURSER WELLNESSWhat Happens If You Have A Gene SNP?A conversation with Dr. Purser

Genetic SNPs are tiny changes in your DNA that can drastically affect how well your enzymes and proteins work. For example, being homozygous for MTHFR C677T leaves that enzyme functioning at only about 30% efficiency, which can drain your energy and impair folate processing. Similarly, errors in SOD genes reduce your body’s ability to neutralize free radicals. While we can’t change your genes, we can work around them by identifying these weaknesses and filling the gaps with targeted nutrition and supplementation—helping your body function closer to its full potential.

PURSER WELLNESSWhat is Intracellular Testing?A conversation with Dr. Purser

…side of your cells. That means uh vitamins, minerals, amino acids, as well as antioxidants. We look at all of these levels, over 100 substances through our intracellular testing. What's the benefit of looking at intracellular levels? Well, …

Most doctors run standard serum blood tests, see a "normal" nutrient level, and send you home. But measuring floating nutrients in your liquid serum is like looking at the paint on a house to see if the plumbing works inside. After reviewing over 40,000 advanced intracellular vitamin lab panels, the truth is clear: intracellular glutathione vs serum levels tell two entirely different stories. Your serum can look completely fine while your cells are completely depleted of the master antioxidant needed to protect your life. The Cytokine Threat When methylation breaks down and homocysteine elevat

An amino acid used in protein synthesis and other metabolic processes. Also called: Methionine Where the cycle begins Methionine is an essential amino acid used to make proteins. It also enters a pathway involving SAM, SAH, and homocysteine…

Supports amino-acid metabolism, neurotransmitter production and hemoglobin synthesis. Also called: Vitamin B6 (Pyridoxine), Pyridoxine A connection between amino acids and brain chemistry B6 helps with chemical messengers and the pathway fr…

Encodes an enzyme involved in fatty-acid metabolism. Also called: Fatty Acid Desaturase 1 / D5D The form of a fatty acid matters Dr. Purser teaches FADS genes as a conversion pathway. FADS1 participates in a delta-5 desaturase step in fatty…

Encodes an enzyme involved in fatty-acid metabolism. Also called: Fatty Acid Desaturase 2 / D6D The form of a fatty acid matters Dr. Purser teaches FADS genes as a conversion pathway. FADS2 participates in a delta-6 desaturase step in fatty…

FOLR2 encodes folate receptor beta, a folate-binding protein expressed in particular cell types, including subsets of immune cells. It is distinct from the FOLR1 receptor and the SLC19A1 reduced folate carrier.

…a-glutamyl hydrolase, which removes glutamate residues from folate compounds. This affects folate handling and helps explain why folate metabolism includes retention and processing as well as intake. Also called: Gamma-Glutamyl Hydrolase Ma…

MTHFD1 helps move folate between forms used for different jobs in the body. Also called: Methylenetetrahydrofolate Dehydrogenase 1 Folate has several working forms Dr. Purser includes MTHFD1 among genes involved in folate interconversion. T…

Makes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine.