NR3C1 encodes the glucocorticoid receptor, which helps tissues respond to cortisol and glucocorticoid medicines. Receptor genetics and measured cortisol levels answer different questions.
Also called: Nuclear Receptor Subfamily 3 Group C Me…
PON1 is discussed in relation to how the body handles some compounds and protects certain fats.
Also called: Paraoxonase 1
A different part of antioxidant handling
PON1 appears in Dr. Purser’s redox and conversion teaching alongside GST and…
PSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.
Also called:…
SERPINE1 makes PAI-1, a protein involved in breaking down blood clots. You may also see PAI4G used for this pathway.
Also called: PAI-1, PAI4G, Plasminogen Activator Inhibitor-1, Plasminogen Activator Inhibitor 1, 4G/5G Polymorphism
Balanci…
SHMT1 connects serine and glycine with folate chemistry.
Also called: Serine Hydroxymethyltransferase 1
Where amino acids meet folate
SHMT1 connects serine and glycine with folate pathways. That is one reason both nutrition and genetics can…
SOD1 helps convert superoxide inside cells as part of the body’s antioxidant defenses.
Also called: Superoxide Dismutase 1
Superoxide defense in its own setting
Dr. Purser teaches SOD as one member of an antioxidant team. SOD1 works primari…
VKORC1 encodes vitamin K epoxide reductase, part of the vitamin K recycling system used in activating clotting proteins. It is not simply a vitamin K receptor.
Also called: Vitamin K Epoxide Reductase Complex Subunit 1
Recycling vitamin K a…
CCL2 encodes MCP-1, a chemokine that attracts monocytes toward sites of immune activity. Recruitment is a different task from the cytokines that activate those cells once they arrive.
Also called:
MCP-1: recruiting monocytes
CCL2 encodes M…
DDAH1 encodes an enzyme that breaks down asymmetric dimethylarginine, or ADMA. ADMA inhibits nitric oxide synthase; DDAH1 is part of its clearance system, not the inhibitor itself.
Also called:
Clearing ADMA helps preserve nitric oxide sig…
HMGB1 normally has functions inside the cell nucleus. When released outside cells in particular settings, it can act as a damage-associated molecular pattern, or DAMP, participating in inflammatory signaling.
Also called:
A cellular protei…
IL4 encodes interleukin-4, a cytokine involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself.
Also calle…
How to make your own essential oil blends?
One of the fun things about essential oils is that you can mix and match them to create your own custom blends. You can experiment with different combinations of oils to suit your personal prefere…
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