MAOA helps break down some chemical messengers. A gene result cannot predict a mood or behavior.
Also called: MAO-A, Monoamine Oxidase A
Neurotransmitter breakdown in context
Dr. Purser places MAOA in the neurotransmitter-breakdown part of …
MAOB encodes monoamine oxidase B, an enzyme involved in breaking down monoamine compounds, including dopamine. It does not simply build dopamine, and a DNA marker is not a neurotransmitter measurement.
Also called: MAO-B, Monoamine Oxidase …
MMP3 encodes matrix metalloproteinase 3, an enzyme involved in breaking down components of the extracellular matrix. Controlled remodeling is part of repair, while excess activity can accompany inflammatory tissue damage.
Also called: Matri…
…ate between forms used for different jobs in the body.
Also called: Methylenetetrahydrofolate Dehydrogenase 1
Folate has several working forms
Dr. Purser includes MTHFD1 among genes involved in folate interconversion. The lesson is that fol…
The homocysteine chapters include MTHFD1L in the wider folate-related genetic map.
Also called: Methylenetetrahydrofolate Dehydrogenase 1-Like
A mitochondrial contribution to one-carbon metabolism
The homocysteine chapters include MTHFD1L i…
Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.
Also called: Methylenetetrahydrofolate Reductase, C677T, A1298C…
Makes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine.
Also called: Methionine Synthase
The B12-dependent step
In Dr. Purser’s teaching map, MTR is the B12-dependent step that converts …
Helps maintain the activity of methionine synthase, connecting B12-related chemistry with homocysteine metabolism.
Also called: Methionine Synthase Reductase
Keeping the remethylation system working
Dr. Purser teaches MTRR alongside MTR bec…
NAT2 encodes N-acetyltransferase 2, which helps process certain drugs and other compounds. Combinations of variants can influence acetylation status; one SNP usually does not tell the entire story.
Also called: N-Acetyltransferase 2
Acetyla…
NOS3 encodes endothelial nitric oxide synthase, which helps blood vessels generate nitric oxide, a signal involved in vascular relaxation. This pathway is distinct from a blood pressure measurement or a diagnosis of vascular disease.
Also c…
NQO1 is the gene name for NAD(P)H Quinone Oxidoreductase 1. Learn what a specific result could mean and what to ask about it.
Also called: NAD(P)H Quinone Oxidoreductase 1
Quinone handling within the redox network
Dr. Purser includes NQO1 i…
NTRK2 encodes TrkB, a receptor involved in responding to neurotrophic signals such as BDNF. These signals support nervous-system function and plasticity. NTRK2 is not a phosphatidylserine absorption transporter.
Also called: Neurotrophic Re…
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