THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “IL-6 and IL-6R: the messenger and its receptor”

A RELATED COURSEYour cytokine starting point

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Gene referenceSep 23, 2026

IL21

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IL21 encodes a cytokine involved in regulating lymphocytes, including B-cell responses. It sits within an immune network that connects T-cell help, antibody responses and inflammatory activity.

Gene referenceSep 23, 2026

HMGB1

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HMGB1 normally has functions inside the cell nucleus. When released outside cells in particular settings, it can act as a damage-associated molecular pattern, or DAMP, participating in inflammatory signaling.

Gene referenceSep 23, 2026

IFNG

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IFNG encodes interferon gamma, a cytokine involved in cellular immune defense and activation of macrophages. It differs from the Th2 signals more often emphasized in allergic responses.

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