THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “NELL-1 and kidney disease”

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Gene referenceSep 23, 2026

IL6

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…measured IL-6 concentration and a diagnosis of inflammatory disease are three different kinds of information. IL6R adds the receptor side of the story. More from the teaching: Inflammation, energy and metabolic overlap In Dr. Purser’s cours…

Gene referenceSep 23, 2026

MMP3

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…lp distinguish mechanical problems from active inflammatory disease. A panel SNP cannot tell you that MMP3 is absent or diagnose arthritis or cancer. A question to bring to your visit Is my joint problem primarily mechanical, inflammatory o…

Gene referenceSep 23, 2026

MTHFD1

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MTHFD1 helps move folate between forms used for different jobs in the body. Also called: Methylenetetrahydrofolate Dehydrogenase 1 Folate has several working forms Dr. Purser includes MTHFD1 among genes involved in folate interconversion. T…

Gene referenceSep 23, 2026

MTHFD1L

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The homocysteine chapters include MTHFD1L in the wider folate-related genetic map. Also called: Methylenetetrahydrofolate Dehydrogenase 1-Like A mitochondrial contribution to one-carbon metabolism The homocysteine chapters include MTHFD1L i…

Gene referenceSep 23, 2026

NR3C1

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NR3C1 encodes the glucocorticoid receptor, which helps tissues respond to cortisol and glucocorticoid medicines. Receptor genetics and measured cortisol levels answer different questions. Also called: Nuclear Receptor Subfamily 3 Group C Me…

Gene referenceSep 23, 2026

PON1

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PON1 is discussed in relation to how the body handles some compounds and protects certain fats. Also called: Paraoxonase 1 A different part of antioxidant handling PON1 appears in Dr. Purser’s redox and conversion teaching alongside GST and…

Gene referenceSep 23, 2026

PTGS2

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…ice should consider the actual response, cardiovascular and kidney risks, gastrointestinal history and other medicines. A question to bring to your visit What has my actual response to anti-inflammatory treatment been, and which risks shape…

Gene referenceSep 23, 2026

SERPINE1

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SERPINE1 makes PAI-1, a protein involved in breaking down blood clots. You may also see PAI4G used for this pathway. Also called: PAI-1, PAI4G, Plasminogen Activator Inhibitor-1, Plasminogen Activator Inhibitor 1, 4G/5G Polymorphism Balanci…

Gene referenceSep 23, 2026

SHMT1

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SHMT1 connects serine and glycine with folate chemistry. Also called: Serine Hydroxymethyltransferase 1 Where amino acids meet folate SHMT1 connects serine and glycine with folate pathways. That is one reason both nutrition and genetics can…

Gene referenceSep 23, 2026

SOD1

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SOD1 helps convert superoxide inside cells as part of the body’s antioxidant defenses. Also called: Superoxide Dismutase 1 Superoxide defense in its own setting Dr. Purser teaches SOD as one member of an antioxidant team. SOD1 works primari…

Gene referenceSep 23, 2026

TNF

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…proach does not replace evaluation of infection, autoimmune disease or another cause of inflammation, and the genotype does not determine a measured TNF level. More from the teaching: Understanding inflammatory amplification Dr. Purser disc…

Gene referenceSep 23, 2026

VDR

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…h supplementation to measured 25-hydroxyvitamin D, calcium, kidney context and the current product list. High-dose vitamin D should not be selected from a SNP alone. The familiar labels are BsmI for rs1544410, TaqI for rs731236 and FokI for…

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