Let’s explore “Genetic variants / SNP findings — lab reference”

… rs1799945, is different from C282Y and from many other HFE variants. Follow the pathway Dr. Purser distinguishes a genetic susceptibility from measured iron overload. He discusses ferritin, transferrin saturation, liver health, and the gr…

…hether folate, B12, homocysteine, choline intake, and liver findings help put the genetic result in context. Two identical alleles do not alone prove a deficiency or mean that liver disease will occur.

…it Ask what each test actually measures and whether it is a genetic result or a protein measurement. Which findings are relevant to your symptoms, and which are useful only with other evidence? The number of flagged entries does not replace…

…r processing, hormone balance, and oxidative stress. Common variants are different from confirmed disease-causing mutations, and a genotype does not directly measure enzyme activity. Bring these questions to your visit Ask how DHEA, DHEAS,…

…rves to be understood alongside kidney function, nutrition, genetics, and other laboratory findings. Your lab results are more than numbers on a page. They are clues that can help you ask better questions about your health. Learn why kid…

…ons to your visit Ask whether the exact finding is a common SNP, a variant of uncertain significance, or a pathogenic variant. Genetic counseling and clinical classification are more useful than interpreting a repair-gene name in isolation.

…mocysteine expert), the missing link for many is MTHFR gene variants (common in ~85% of people). These impair folate processing → elevated homocysteine → massive inflammation and cytokine storms (IL-6, TNF-α, IL-17, etc.). High homocystein…

PURSER WELLNESSMTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss From the reading room

…irm the link: MTHFR C677T and A1298C polymorphisms increase genetic susceptibility to rheumatoid arthritis (especially in Asian populations) and systemic lupus erythematosus. In multiple sclerosis, the MTHFR 677TT genotype correlates with h…

… kidney or blood pressure issues. Homocysteine isn’t just a lab number — it’s a toxic byproduct that drives inflammation through cytokines like MCP-1 and IL-8, damaging blood vessels and disrupting hormones. Dr. Purser’s research found up t…

…, leading to inefficient methylation. There are two primary variants of the mutation, C677T and A1298C. People can have one or two copies of each mutation (from either or both parents), affecting the function of the MTHFR enzyme to varying …

PURSER WELLNESSA Natural Approach to Lowering High Blood PressureFrom the reading room

… due to factors such as a lack of exercise, poor diet, or a genetic predisposition to high blood pressure. A 2020 study showed that variations in the CYP24A1 gene can have a strong impact on a person’s risk of developing chronic high blood …

…ITY, GARDEN OF LIFE RAW FOR WOMEN OVER 50, YLEO LIFE 9. 7. GENETIC GLUTEN INTOLERANCE: HLA DQA 1 or 2. Heterozygous vs homozygous. Available on our PRO7 GENETIC TEST. (The HLA-DQA1 gene is part of a family of genes called the human leukocy…