THE PURSER WELLNESS ENCYCLOPEDIA
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What’s searchable?…he reduced folate carrier, a protein involved in transporting folates into cells. Also called: RFC1, reduced folate carrier, folate transport Folate transport is part of the story Dr. Purser’s folate map includes transport as well as conver…
…aline phosphatase can deserve a different evaluation from a general nutrient deficiency. Also called: B6, bone mineralization and alkaline phosphatase ALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme important to bone and to…
…CL11 encodes eotaxin-1, a chemokine best known for attracting eosinophils. Its receptor relationships connect it to allergic inflammation as well as broader research into immune signaling. Also called: Eotaxin-1 and eosinophil recruitment …
CCL2 encodes MCP-1, a chemokine that attracts monocytes toward sites of immune activity. Recruitment is a different task from the cytokines that activate those cells once they arrive. Also called: MCP-1: recruiting monocytes CCL2 encodes M…
CCL3 encodes MIP-1 alpha, a chemokine involved in attracting and activating immune cells. It is related to CCL4, or MIP-1 beta, but the two genes and proteins are distinct. Also called: MIP-1 alpha and the chemokine cluster CCL3 encodes MI…
CCL4 encodes MIP-1 beta, a chemokine involved in attracting immune cells. It participates in a recruitment network that includes CCL2, CXCL8 and related chemokines. Also called: MIP-1 beta and overlapping recruitment signals CCL4 encodes M…
…direct immune-cell movement. Chemokines tell cells where to go, which is different from measuring the total strength of an immune response. Also called: RANTES and immune-cell recruitment CCL5, also called RANTES, is a chemokine that helps…
…participates in communication between immune cells, including T-cell help for B-cell responses. Its partner is CD40 ligand, encoded by CD40LG. Also called: A conversation between immune cells CD40 encodes a receptor that participates in co…
CD40LG encodes CD40 ligand, which binds CD40 and supports communication needed for effective antibody responses. It is on the X chromosome, which changes how some genetic results must be interpreted. Also called: The ligand that helps acti…
… of HDL and other lipid particles is more complex than a single cholesterol number. Also called: Moving cholesterol between lipoproteins CETP transfers cholesteryl esters between lipoprotein particles. This helps explain why the balance of…
CXCL13 is a chemokine that attracts cells expressing CXCR5, including B cells. This pairing helps organize immune-cell traffic in lymphoid tissues and some chronic inflammatory settings. Also called: Guiding B cells to organized immune sit…
CXCL8 is the gene for IL-8, a chemokine involved in recruiting and activating neutrophils. IL-8 is the protein nickname; CXCL8 is the gene name a DNA report may use. Also called: IL-8: bringing neutrophils to the response CXCL8 is the gene…
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